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Kidney Transplantation in Patients With the History of SARS-CoV-2 Infection

Background. The aim of this study is to present the experience and results of kidney transplantation in patients with the history of SARS-CoV-2 infection. Methods. We retrospectively analyzed waitlisted patients who had a history of SARS-CoV-2 infection and offered a kidney transplant between March...

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Autores principales: Juric, Ivana, Katalinic, Lea, Furic-Cunko, Vesna, Basic-Jukic, Nikolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444488/
https://www.ncbi.nlm.nih.gov/pubmed/36184341
http://dx.doi.org/10.1016/j.transproceed.2022.08.015
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author Juric, Ivana
Katalinic, Lea
Furic-Cunko, Vesna
Basic-Jukic, Nikolina
author_facet Juric, Ivana
Katalinic, Lea
Furic-Cunko, Vesna
Basic-Jukic, Nikolina
author_sort Juric, Ivana
collection PubMed
description Background. The aim of this study is to present the experience and results of kidney transplantation in patients with the history of SARS-CoV-2 infection. Methods. We retrospectively analyzed waitlisted patients who had a history of SARS-CoV-2 infection and offered a kidney transplant between March 2020 and December 2021. Results. Of the 97 waitlisted potential kidney transplant recipients who were offered a kidney, 13 (13.4%) had a history of SARS-CoV-2 infection. All patients were tested negative for SARS-CoV-2 at the time of the kidney offer. Successful transplantation was performed in 9 patients (5 male; average age was 40.8 years), with the average time between SARS-CoV-2 infection and transplantation of 8 months. Four of 13 patients with a history of SARS-CoV-2 infection were finally not transplanted, with 2 patients not eligible for transplantation due to significant post-COVID findings in routine pretransplant chest CT scans, and 2 patients were not transplanted because of poor donor organ quality. Conclusions. Kidney transplantation after SARS-CoV-2 infection is possible in a setting of full recovery from acute infection, negative PCR test, and no pneumonic infiltrates on chest CT scan. A growing number of waitlisted patients with a history of SARS-CoV-2 infection imposes the need for decision-making tools and guidelines for risk/benefit assessment in these patients.
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spelling pubmed-94444882022-09-06 Kidney Transplantation in Patients With the History of SARS-CoV-2 Infection Juric, Ivana Katalinic, Lea Furic-Cunko, Vesna Basic-Jukic, Nikolina Transplant Proc Article Background. The aim of this study is to present the experience and results of kidney transplantation in patients with the history of SARS-CoV-2 infection. Methods. We retrospectively analyzed waitlisted patients who had a history of SARS-CoV-2 infection and offered a kidney transplant between March 2020 and December 2021. Results. Of the 97 waitlisted potential kidney transplant recipients who were offered a kidney, 13 (13.4%) had a history of SARS-CoV-2 infection. All patients were tested negative for SARS-CoV-2 at the time of the kidney offer. Successful transplantation was performed in 9 patients (5 male; average age was 40.8 years), with the average time between SARS-CoV-2 infection and transplantation of 8 months. Four of 13 patients with a history of SARS-CoV-2 infection were finally not transplanted, with 2 patients not eligible for transplantation due to significant post-COVID findings in routine pretransplant chest CT scans, and 2 patients were not transplanted because of poor donor organ quality. Conclusions. Kidney transplantation after SARS-CoV-2 infection is possible in a setting of full recovery from acute infection, negative PCR test, and no pneumonic infiltrates on chest CT scan. A growing number of waitlisted patients with a history of SARS-CoV-2 infection imposes the need for decision-making tools and guidelines for risk/benefit assessment in these patients. Published by Elsevier Inc. 2022-12 2022-09-06 /pmc/articles/PMC9444488/ /pubmed/36184341 http://dx.doi.org/10.1016/j.transproceed.2022.08.015 Text en © 2022 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Juric, Ivana
Katalinic, Lea
Furic-Cunko, Vesna
Basic-Jukic, Nikolina
Kidney Transplantation in Patients With the History of SARS-CoV-2 Infection
title Kidney Transplantation in Patients With the History of SARS-CoV-2 Infection
title_full Kidney Transplantation in Patients With the History of SARS-CoV-2 Infection
title_fullStr Kidney Transplantation in Patients With the History of SARS-CoV-2 Infection
title_full_unstemmed Kidney Transplantation in Patients With the History of SARS-CoV-2 Infection
title_short Kidney Transplantation in Patients With the History of SARS-CoV-2 Infection
title_sort kidney transplantation in patients with the history of sars-cov-2 infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444488/
https://www.ncbi.nlm.nih.gov/pubmed/36184341
http://dx.doi.org/10.1016/j.transproceed.2022.08.015
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