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Intratympanic corticosteroid for sudden hearing loss: does it really work?()()

INTRODUCTION: Sudden deafness is characterized by an abrupt hearing loss of at least 30 dB in three sequential frequencies in the standard pure tone audiogram over three days or less. Treatment is based on its etiology, and oral corticosteroids are widely used. Intratympanic corticosteroids are incl...

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Autores principales: Barreto, Monique Antunes de Souza Chelminski, Ledesma, Aleluia Lima Losno, de Oliveira, Carlos Augusto Costa Pires, Bahmad Jr, Fayez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444616/
https://www.ncbi.nlm.nih.gov/pubmed/26873148
http://dx.doi.org/10.1016/j.bjorl.2015.06.007
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author Barreto, Monique Antunes de Souza Chelminski
Ledesma, Aleluia Lima Losno
de Oliveira, Carlos Augusto Costa Pires
Bahmad Jr, Fayez
author_facet Barreto, Monique Antunes de Souza Chelminski
Ledesma, Aleluia Lima Losno
de Oliveira, Carlos Augusto Costa Pires
Bahmad Jr, Fayez
author_sort Barreto, Monique Antunes de Souza Chelminski
collection PubMed
description INTRODUCTION: Sudden deafness is characterized by an abrupt hearing loss of at least 30 dB in three sequential frequencies in the standard pure tone audiogram over three days or less. Treatment is based on its etiology, and oral corticosteroids are widely used. Intratympanic corticosteroids are included as primary or secondary treatment when there is no improvement with the use of oral corticosteroids. OBJECTIVE: To determine the effectiveness of therapy with intratympanic steroids in sudden deafness. METHODS: A systematic review was performed of publications on the topic in the databases of PubMed/MEDLINE, with the keywords: sudden deafness, sudden hearing loss, and corticosteroids. RESULTS: Thirty scientific studies were analyzed. As to the objectives of the study analyzed, 76.7% sought to evaluate the use of intratympanic therapy salvage after failure to conventional treatment, and intratympanic therapy was used as the primary treatment 23.3% of the studies. CONCLUSION: Intratympanic corticosteroid therapy is prescribed primarily when there is failure of conventional therapy and when it is limited to use systemic corticosteroids, such as the diabetic patient.
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spelling pubmed-94446162022-09-09 Intratympanic corticosteroid for sudden hearing loss: does it really work?()() Barreto, Monique Antunes de Souza Chelminski Ledesma, Aleluia Lima Losno de Oliveira, Carlos Augusto Costa Pires Bahmad Jr, Fayez Braz J Otorhinolaryngol Review Article INTRODUCTION: Sudden deafness is characterized by an abrupt hearing loss of at least 30 dB in three sequential frequencies in the standard pure tone audiogram over three days or less. Treatment is based on its etiology, and oral corticosteroids are widely used. Intratympanic corticosteroids are included as primary or secondary treatment when there is no improvement with the use of oral corticosteroids. OBJECTIVE: To determine the effectiveness of therapy with intratympanic steroids in sudden deafness. METHODS: A systematic review was performed of publications on the topic in the databases of PubMed/MEDLINE, with the keywords: sudden deafness, sudden hearing loss, and corticosteroids. RESULTS: Thirty scientific studies were analyzed. As to the objectives of the study analyzed, 76.7% sought to evaluate the use of intratympanic therapy salvage after failure to conventional treatment, and intratympanic therapy was used as the primary treatment 23.3% of the studies. CONCLUSION: Intratympanic corticosteroid therapy is prescribed primarily when there is failure of conventional therapy and when it is limited to use systemic corticosteroids, such as the diabetic patient. Elsevier 2015-11-06 /pmc/articles/PMC9444616/ /pubmed/26873148 http://dx.doi.org/10.1016/j.bjorl.2015.06.007 Text en © 2015 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Barreto, Monique Antunes de Souza Chelminski
Ledesma, Aleluia Lima Losno
de Oliveira, Carlos Augusto Costa Pires
Bahmad Jr, Fayez
Intratympanic corticosteroid for sudden hearing loss: does it really work?()()
title Intratympanic corticosteroid for sudden hearing loss: does it really work?()()
title_full Intratympanic corticosteroid for sudden hearing loss: does it really work?()()
title_fullStr Intratympanic corticosteroid for sudden hearing loss: does it really work?()()
title_full_unstemmed Intratympanic corticosteroid for sudden hearing loss: does it really work?()()
title_short Intratympanic corticosteroid for sudden hearing loss: does it really work?()()
title_sort intratympanic corticosteroid for sudden hearing loss: does it really work?()()
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444616/
https://www.ncbi.nlm.nih.gov/pubmed/26873148
http://dx.doi.org/10.1016/j.bjorl.2015.06.007
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