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Partial laryngectomy in glottic cancer: complications and oncological results()

INTRODUCTION: Most patients with laryngeal carcinoma present tumors in the glottis that can be treated by different treatment modalities. Some authors consider open partial laryngectomy as obsolete, while others still deem this as a viable and cost-efficient option. OBJECTIVES: To compare the oncolo...

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Autores principales: Graciano, Agnaldo José, Sonagli, Marina, da Silva, Ana Gabriela Clemente, Fischer, Carlos Augusto, Chone, Carlos Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444659/
https://www.ncbi.nlm.nih.gov/pubmed/26614047
http://dx.doi.org/10.1016/j.bjorl.2015.05.011
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author Graciano, Agnaldo José
Sonagli, Marina
da Silva, Ana Gabriela Clemente
Fischer, Carlos Augusto
Chone, Carlos Takahiro
author_facet Graciano, Agnaldo José
Sonagli, Marina
da Silva, Ana Gabriela Clemente
Fischer, Carlos Augusto
Chone, Carlos Takahiro
author_sort Graciano, Agnaldo José
collection PubMed
description INTRODUCTION: Most patients with laryngeal carcinoma present tumors in the glottis that can be treated by different treatment modalities. Some authors consider open partial laryngectomy as obsolete, while others still deem this as a viable and cost-efficient option. OBJECTIVES: To compare the oncological and functional results of a series of patients undergoing partial laryngectomy vs. external radiotherapy for the treatment of glottic cancer. METHODS: Historical cohort study with a series of glottic carcinoma patients undergoing partial laryngectomy or external radiotherapy during a period of ten years. RESULTS: Sixty-two patients with glottic carcinoma were included. Group A comprised those submitted to partial laryngectomy (n = 30), and Group B, those who underwent radiotherapy (n = 32). They were homogeneous in the comparison of mean age, 56.4 vs. 60.4 years (p = 0.12) and distribution in pathological stage (p = 0.91). With regard to oncological outcome, there were no differences in distant metastasis rates, or second primary tumor between groups (p = 1.0), as well as in disease-free time, laryngeal rescue-free time, and overall five-year survival. Severe complication rates were also similar between groups. CONCLUSION: Open partial laryngectomy had complication rates and oncological results similar to those of radiotherapy for patients with glottic carcinomas and should still be considered among the main available therapeutic options.
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spelling pubmed-94446592022-09-09 Partial laryngectomy in glottic cancer: complications and oncological results() Graciano, Agnaldo José Sonagli, Marina da Silva, Ana Gabriela Clemente Fischer, Carlos Augusto Chone, Carlos Takahiro Braz J Otorhinolaryngol Original Article INTRODUCTION: Most patients with laryngeal carcinoma present tumors in the glottis that can be treated by different treatment modalities. Some authors consider open partial laryngectomy as obsolete, while others still deem this as a viable and cost-efficient option. OBJECTIVES: To compare the oncological and functional results of a series of patients undergoing partial laryngectomy vs. external radiotherapy for the treatment of glottic cancer. METHODS: Historical cohort study with a series of glottic carcinoma patients undergoing partial laryngectomy or external radiotherapy during a period of ten years. RESULTS: Sixty-two patients with glottic carcinoma were included. Group A comprised those submitted to partial laryngectomy (n = 30), and Group B, those who underwent radiotherapy (n = 32). They were homogeneous in the comparison of mean age, 56.4 vs. 60.4 years (p = 0.12) and distribution in pathological stage (p = 0.91). With regard to oncological outcome, there were no differences in distant metastasis rates, or second primary tumor between groups (p = 1.0), as well as in disease-free time, laryngeal rescue-free time, and overall five-year survival. Severe complication rates were also similar between groups. CONCLUSION: Open partial laryngectomy had complication rates and oncological results similar to those of radiotherapy for patients with glottic carcinomas and should still be considered among the main available therapeutic options. Elsevier 2015-10-19 /pmc/articles/PMC9444659/ /pubmed/26614047 http://dx.doi.org/10.1016/j.bjorl.2015.05.011 Text en © 2015 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Graciano, Agnaldo José
Sonagli, Marina
da Silva, Ana Gabriela Clemente
Fischer, Carlos Augusto
Chone, Carlos Takahiro
Partial laryngectomy in glottic cancer: complications and oncological results()
title Partial laryngectomy in glottic cancer: complications and oncological results()
title_full Partial laryngectomy in glottic cancer: complications and oncological results()
title_fullStr Partial laryngectomy in glottic cancer: complications and oncological results()
title_full_unstemmed Partial laryngectomy in glottic cancer: complications and oncological results()
title_short Partial laryngectomy in glottic cancer: complications and oncological results()
title_sort partial laryngectomy in glottic cancer: complications and oncological results()
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444659/
https://www.ncbi.nlm.nih.gov/pubmed/26614047
http://dx.doi.org/10.1016/j.bjorl.2015.05.011
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