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Cancer treatment in determination of hearing loss()()
INTRODUCTION: Chemotherapy and radiotherapy in oncology have repercussions in hearing health, and can damage structures of the inner ear. These repercussions usually, result in a bilateral and irreversible hearing loss. OBJECTIVE: To identify sensorineural hearing loss cases with complaints of tinni...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444677/ https://www.ncbi.nlm.nih.gov/pubmed/26549572 http://dx.doi.org/10.1016/j.bjorl.2014.12.010 |
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author | Oliveira, Priscila Feliciano de Oliveira, Camila Silva Andrade, Joice Santos do Carmo Santos, Tamara Figueiredo de Oliveira-Barreto, Aline Cabral |
author_facet | Oliveira, Priscila Feliciano de Oliveira, Camila Silva Andrade, Joice Santos do Carmo Santos, Tamara Figueiredo de Oliveira-Barreto, Aline Cabral |
author_sort | Oliveira, Priscila Feliciano de |
collection | PubMed |
description | INTRODUCTION: Chemotherapy and radiotherapy in oncology have repercussions in hearing health, and can damage structures of the inner ear. These repercussions usually, result in a bilateral and irreversible hearing loss. OBJECTIVE: To identify sensorineural hearing loss cases with complaints of tinnitus and difficulty in speech understanding and investigate their relationship with the types of chemotherapy and radiotherapy the patients received. METHODS: Cross-sectional, clinical, observational, analytical, historical cohort study of 58 subjects treated in a public hospital in the state of Sergipe, diagnosed with neoplasia. The subjects were submitted to anamnesis, conventional pure tone audiometry, and speech recognition threshold. RESULTS: Of the 116 ears, 25.9% presented sensorioneural hearing loss characterized by changes in high frequencies. There was a positive correlation between hearing loss and the association of chemotherapy and radiotherapy (p = 0.035; R = 0.196). The auditory complaint analysis shows that most of the subjects had tinnitus and speech understanding difficulty, even with a normal auditory threshold. CONCLUSIONS: Cancer treatment causes hearing loss, associated with the administration of chemotherapy and radiotherapy. Cyclophosphamide increased the risk of causing hearing loss. Complaints of tinnitus and speech understanding difficulty were observed. |
format | Online Article Text |
id | pubmed-9444677 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94446772022-09-09 Cancer treatment in determination of hearing loss()() Oliveira, Priscila Feliciano de Oliveira, Camila Silva Andrade, Joice Santos do Carmo Santos, Tamara Figueiredo de Oliveira-Barreto, Aline Cabral Braz J Otorhinolaryngol Original Article INTRODUCTION: Chemotherapy and radiotherapy in oncology have repercussions in hearing health, and can damage structures of the inner ear. These repercussions usually, result in a bilateral and irreversible hearing loss. OBJECTIVE: To identify sensorineural hearing loss cases with complaints of tinnitus and difficulty in speech understanding and investigate their relationship with the types of chemotherapy and radiotherapy the patients received. METHODS: Cross-sectional, clinical, observational, analytical, historical cohort study of 58 subjects treated in a public hospital in the state of Sergipe, diagnosed with neoplasia. The subjects were submitted to anamnesis, conventional pure tone audiometry, and speech recognition threshold. RESULTS: Of the 116 ears, 25.9% presented sensorioneural hearing loss characterized by changes in high frequencies. There was a positive correlation between hearing loss and the association of chemotherapy and radiotherapy (p = 0.035; R = 0.196). The auditory complaint analysis shows that most of the subjects had tinnitus and speech understanding difficulty, even with a normal auditory threshold. CONCLUSIONS: Cancer treatment causes hearing loss, associated with the administration of chemotherapy and radiotherapy. Cyclophosphamide increased the risk of causing hearing loss. Complaints of tinnitus and speech understanding difficulty were observed. Elsevier 2015-10-17 /pmc/articles/PMC9444677/ /pubmed/26549572 http://dx.doi.org/10.1016/j.bjorl.2014.12.010 Text en © 2015 Associac¸ão Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Original Article Oliveira, Priscila Feliciano de Oliveira, Camila Silva Andrade, Joice Santos do Carmo Santos, Tamara Figueiredo de Oliveira-Barreto, Aline Cabral Cancer treatment in determination of hearing loss()() |
title | Cancer treatment in determination of hearing loss()() |
title_full | Cancer treatment in determination of hearing loss()() |
title_fullStr | Cancer treatment in determination of hearing loss()() |
title_full_unstemmed | Cancer treatment in determination of hearing loss()() |
title_short | Cancer treatment in determination of hearing loss()() |
title_sort | cancer treatment in determination of hearing loss()() |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444677/ https://www.ncbi.nlm.nih.gov/pubmed/26549572 http://dx.doi.org/10.1016/j.bjorl.2014.12.010 |
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