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Thyroid leiomyosarcoma: presentation of two cases and review of the literature()

INTRODUCTION: Leiomyosarcoma is a tumor which is rarely seen in the thyroid gland. The diagnosis may be difficult and the treatment is controversial. OBJECTIVE: The objective of the study is to review the literature about a rare malignant disease of the thyroid gland which has high mortality. METHOD...

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Autores principales: Şahin, Mehmet İlhan, Vural, Alperen, Yüce, İmdat, Çağlı, Sedat, Deniz, Kemal, Güney, Ercihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444791/
https://www.ncbi.nlm.nih.gov/pubmed/27080750
http://dx.doi.org/10.1016/j.bjorl.2015.11.020
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author Şahin, Mehmet İlhan
Vural, Alperen
Yüce, İmdat
Çağlı, Sedat
Deniz, Kemal
Güney, Ercihan
author_facet Şahin, Mehmet İlhan
Vural, Alperen
Yüce, İmdat
Çağlı, Sedat
Deniz, Kemal
Güney, Ercihan
author_sort Şahin, Mehmet İlhan
collection PubMed
description INTRODUCTION: Leiomyosarcoma is a tumor which is rarely seen in the thyroid gland. The diagnosis may be difficult and the treatment is controversial. OBJECTIVE: The objective of the study is to review the literature about a rare malignant disease of the thyroid gland which has high mortality. METHODS: Two cases of thyroid leiomyosarcoma are presented and the previous 23 cases in the current literature are reviewed. RESULTS: A total of 25 cases of thyroid leiomyosarcoma are reviewed; the most common complaint was rapidly growing anterior neck mass, and ten of the 25 patients had distant metastasis at the initial admission. Fifteen of the 25 patients died with the disease in the first 12 months after the diagnosis. CONCLUSION: The differential diagnosis of thyroid leiomyosarcoma is important and should be performed with other malignancies of the gland, especially with anaplastic carcinoma. The prognosis is poor and there is no consensus regarding the treatment.
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spelling pubmed-94447912022-09-09 Thyroid leiomyosarcoma: presentation of two cases and review of the literature() Şahin, Mehmet İlhan Vural, Alperen Yüce, İmdat Çağlı, Sedat Deniz, Kemal Güney, Ercihan Braz J Otorhinolaryngol Review Article INTRODUCTION: Leiomyosarcoma is a tumor which is rarely seen in the thyroid gland. The diagnosis may be difficult and the treatment is controversial. OBJECTIVE: The objective of the study is to review the literature about a rare malignant disease of the thyroid gland which has high mortality. METHODS: Two cases of thyroid leiomyosarcoma are presented and the previous 23 cases in the current literature are reviewed. RESULTS: A total of 25 cases of thyroid leiomyosarcoma are reviewed; the most common complaint was rapidly growing anterior neck mass, and ten of the 25 patients had distant metastasis at the initial admission. Fifteen of the 25 patients died with the disease in the first 12 months after the diagnosis. CONCLUSION: The differential diagnosis of thyroid leiomyosarcoma is important and should be performed with other malignancies of the gland, especially with anaplastic carcinoma. The prognosis is poor and there is no consensus regarding the treatment. Elsevier 2016-03-29 /pmc/articles/PMC9444791/ /pubmed/27080750 http://dx.doi.org/10.1016/j.bjorl.2015.11.020 Text en © 2016 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review Article
Şahin, Mehmet İlhan
Vural, Alperen
Yüce, İmdat
Çağlı, Sedat
Deniz, Kemal
Güney, Ercihan
Thyroid leiomyosarcoma: presentation of two cases and review of the literature()
title Thyroid leiomyosarcoma: presentation of two cases and review of the literature()
title_full Thyroid leiomyosarcoma: presentation of two cases and review of the literature()
title_fullStr Thyroid leiomyosarcoma: presentation of two cases and review of the literature()
title_full_unstemmed Thyroid leiomyosarcoma: presentation of two cases and review of the literature()
title_short Thyroid leiomyosarcoma: presentation of two cases and review of the literature()
title_sort thyroid leiomyosarcoma: presentation of two cases and review of the literature()
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444791/
https://www.ncbi.nlm.nih.gov/pubmed/27080750
http://dx.doi.org/10.1016/j.bjorl.2015.11.020
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