Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns

The formyl peptide receptor 1 (FPR1) is primarily responsible for detection of short peptides bearing N-formylated methionine (fMet) that are characteristic of protein synthesis in bacteria and mitochondria. As a result, FPR1 is critical to phagocyte migration and activation in bacterial infection,...

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Detalles Bibliográficos
Autores principales: Chen, Geng, Wang, Xiankun, Liao, Qiwen, Ge, Yunjun, Jiao, Haizhan, Chen, Qiang, Liu, Yezhou, Lyu, Wenping, Zhu, Lizhe, van Zundert, Gydo C. P., Robertson, Michael J., Skiniotis, Georgios, Du, Yang, Hu, Hongli, Ye, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445081/
https://www.ncbi.nlm.nih.gov/pubmed/36064945
http://dx.doi.org/10.1038/s41467-022-32822-y

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