The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity

The striatum is primarily composed of two types of medium spiny neurons (MSNs) expressing either D1- or D2-type dopamine receptors. However, the fate determination of these two types of neurons is not fully understood. Here, we found that D1 MSNs undergo fate switching to D2 MSNs in the absence of Z...

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Detalles Bibliográficos
Autores principales: Shang, Zicong, Yang, Lin, Wang, Ziwu, Tian, Yu, Gao, Yanjing, Su, Zihao, Guo, Rongliang, Li, Weiwei, Liu, Guoping, Li, Xiaosu, Yang, Zhengang, Li, Zhenmeiyu, Zhang, Zhuangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445169/
https://www.ncbi.nlm.nih.gov/pubmed/36081908
http://dx.doi.org/10.3389/fcell.2022.948331

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