Cargando…

Oroxylin A ameliorates AKI-to-CKD transition through maintaining PPARα-BNIP3 signaling-mediated mitochondrial homeostasis

Background: Acute kidney injury (AKI) occurs in approximately 7–18% of all hospitalizations, but there are currently no effective drug therapy for preventing AKI or delaying its progression to chronic kidney disease (CKD). Recent studies have shown that Scutellaria baicalensis, a traditional Chinese...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Mengying, Qin, Shaozong, Xiong, Jiachuan, Xin, Wang, Guan, Xu, Gong, Shuiqin, Chen, Jing, Liu, Yong, Zhang, Bo, Zhao, Jinghong, Huang, Yinghui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445212/ https://www.ncbi.nlm.nih.gov/pubmed/36081929 http://dx.doi.org/10.3389/fphar.2022.935937

Ejemplares similares

Activation of EP4 alleviates AKI-to-CKD transition through inducing CPT2-mediated lipophagy in renal macrophages
por: Guan, Xu, et al.
Publicado: (2022)

REST contributes to AKI-to-CKD transition through inducing ferroptosis in renal tubular epithelial cells
por: Gong, Shuiqin, et al.
Publicado: (2023)

The Intestinal Microbiota and Metabolites in the Gut-Kidney-Heart Axis of Chronic Kidney Disease
por: Huang, Yinghui, et al.
Publicado: (2022)

IL-18 deficiency ameliorates the progression from AKI to CKD
por: Luan, Junjun, et al.
Publicado: (2022)

Infectious consequences of the AKI-to-CKD transition
por: Sánchez Horrillo, Ana, et al.
Publicado: (2022)

Oroxylin a Attenuates Limb Ischemia by Promoting Angiogenesis via Modulation of Endothelial Cell Migration
por: Zhang, Lusha, et al.
Publicado: (2021)

Antidepressant-like activity of oroxylin A in mice models of depression: A behavioral and neurobiological characterization
por: Wu, Zhong-hua, et al.
Publicado: (2022)

Oroxylin A, but Not Vasopressin, Ameliorates Cardiac Dysfunction of Endotoxemic Rats
por: Liu, Chin-Hung, et al.
Publicado: (2012)

A potential link between fibroblast growth factor-23 and the progression of AKI to CKD
por: Lu, Yinghui, et al.
Publicado: (2023)

Dynamic signature of lymphangiogenesis during AKI and CKD
por: Zarjou, Abolfazl, et al.
Publicado: (2019)

The potential roles of galectin-3 in AKI and CKD
por: Wang, Fengyun, et al.
Publicado: (2023)

The AKI-to-CKD Transition: The Role of Uremic Toxins
por: André, Camille, et al.
Publicado: (2023)

Selective Wnt/β-Catenin Pathway Activation Concomitant With Sustained Overexpression of miR-21 is Responsible for Aristolochic Acid-Induced AKI-to-CKD Transition
por: Kuang, Qing, et al.
Publicado: (2021)

Activated Platelets, the Booster of Chronic Kidney Disease and Cardiovascular Complications
por: Gong, Shuiqin, et al.
Publicado: (2022)

A Candidate Drug Screen Strategy: The Discovery of Oroxylin A in Scutellariae Radix Against Sepsis via the Correlation Analysis Between Plant Metabolomics and Pharmacodynamics
por: Han, Lingyu, et al.
Publicado: (2022)

Meta-analysis of AKI to CKD transition in perioperative patients
por: M. Abdala, Pedro, et al.
Publicado: (2021)

Epigenetic memory contributing to the pathogenesis of AKI-to-CKD transition
por: Tanemoto, Fumiaki, et al.
Publicado: (2022)

From AKI to CKD: Maladaptive Repair and the Underlying Mechanisms
por: Wang, Zhiwen, et al.
Publicado: (2022)

Recombinant Long-Acting Thioredoxin Ameliorates AKI to CKD Transition via Modulating Renal Oxidative Stress and Inflammation
por: Nishida, Kento, et al.
Publicado: (2021)

The COVID-19 nephrology compendium: AKI, CKD, ESKD and transplantation
por: Kant, Sam, et al.
Publicado: (2020)

Glycyrrhetinic Acid Maintains Intestinal Homeostasis via HuR
por: Chen, Gang, et al.
Publicado: (2019)

Phytochemicals Mediate Autophagy Against Osteoarthritis by Maintaining Cartilage Homeostasis
por: Tian, Zheng, et al.
Publicado: (2021)

Sepsis-induced AKI: From pathogenesis to therapeutic approaches
por: He, Fang-Fang, et al.
Publicado: (2022)

Antiplatelet therapy for the prevention of atherosclerosis in chronic kidney disease (ALTAS-CKD) patients: study protocol for a randomized clinical trial
por: Xiong, Jiachuan, et al.
Publicado: (2021)

PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules
por: Lyu, Zhongshi, et al.
Publicado: (2018)

RIPK3-MLKL-mediated necroinflammation contributes to AKI progression to CKD
por: Chen, Hui, et al.
Publicado: (2018)

EGFR drives the progression of AKI to CKD through HIPK2 overexpression
por: Xu, Luyang, et al.
Publicado: (2019)

The Road from AKI to CKD: Molecular Mechanisms and Therapeutic Targets of Ferroptosis
por: Guo, Runzhi, et al.
Publicado: (2023)

A Mixture of Baicalein, Wogonin, and Oroxylin-A Inhibits EMT in the A549 Cell Line via the PI3K/AKT-TWIST1-Glycolysis Pathway
por: Cao, Hui-Juan, et al.
Publicado: (2022)

Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes
por: Tu, Jun, et al.
Publicado: (2020)

Ferroptosis and Acute Kidney Injury (AKI): Molecular Mechanisms and Therapeutic Potentials
por: Feng, Qi, et al.
Publicado: (2022)

Shenmai Injection Protects Against Doxorubicin-Induced Cardiotoxicity via Maintaining Mitochondrial Homeostasis
por: Li, Lin, et al.
Publicado: (2020)

The critical role of FXR is associated with the regulation of autophagy and apoptosis in the progression of AKI to CKD
por: Kim, Dong-Hyun, et al.
Publicado: (2021)

Uremic Toxins and Protein-Bound Therapeutics in AKI and CKD: Up-to-Date Evidence
por: Chen, Jia-Huang, et al.
Publicado: (2021)

PPARα Ameliorates Doxorubicin-Induced Cardiotoxicity by Reducing Mitochondria-Dependent Apoptosis via Regulating MEOX1
por: Wang, Wei, et al.
Publicado: (2020)

Bailing capsule (Cordyceps sinensis) ameliorates renal triglyceride accumulation through the PPARα pathway in diabetic rats
por: Zhang, Qian, et al.
Publicado: (2022)

Deciphering the active constituents of Dabushen decoction of ameliorating osteoarthritis via PPARγ preservation by targeting DNMT1
por: Qiu, Lu, et al.
Publicado: (2022)

Hydrogen-Rich Saline Alleviates Kidney Fibrosis Following AKI and Retains Klotho Expression
por: Chen, Jing, et al.
Publicado: (2017)

Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy Metabolism
por: Zhang, Xiaoying, et al.
Publicado: (2021)

Icariside II Ameliorates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Inhibiting the Amyloidogenic Pathway: Involvement of BDNF/TrkB/CREB Signaling and Up-Regulation of PPARα and PPARγ in Rats
por: Yin, Caixia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tftgjuuk6ft9q00tddjufq3qnl