FLT3LG and IFITM3P6 consolidate T cell activity in the bone marrow microenvironment and are prognostic factors in acute myelocytic leukemia

Acute myelocytic leukemia (AML) is a malignancy of the stem cell precursors of the myeloid lineage. CD4+ and CD8+ T cells play pivotal roles in influencing AML progression but are functionally suppressed in the bone marrow microenvironment. We aimed to find hub genes related to T cell exhaustion and...

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Detalles Bibliográficos
Autores principales: Chen, Haiyan, Wu, Meng, Xia, Hongping, Du, Songjie, Zhou, Guoren, Long, Guangfeng, Zhu, Yanan, Huang, Xu, Yang, Daheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445253/
https://www.ncbi.nlm.nih.gov/pubmed/36081495
http://dx.doi.org/10.3389/fimmu.2022.980911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445253/
https://www.ncbi.nlm.nih.gov/pubmed/36081495
http://dx.doi.org/10.3389/fimmu.2022.980911

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