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Role of 3'-Deoxy-3'-[(18)F] Fluorothymidine Positron Emission Tomography-Computed Tomography as a Predictive Biomarker in Argininosuccinate Synthetase 1-Deficient Thoracic Cancers Treated With Pegargiminase

INTRODUCTION: Pegargiminase (ADI-PEG 20I) degrades arginine in patients with argininosuccinate synthetase 1-deficient malignant pleural mesothelioma (MPM) and NSCLC. Imaging with proliferation biomarker 3'-deoxy-3'-[(18)F] fluorothymidine ((18)F-FLT) positron emission tomography (PET)-comp...

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Detalles Bibliográficos
Autores principales: Szyszko, Teresa A., Dunn, Joel T., Phillips, Melissa M., Bomalaski, John, Sheaff, Michael T., Ellis, Steve, Pike, Lucy, Goh, Vicky, Cook, Gary J.R., Szlosarek, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445378/
https://www.ncbi.nlm.nih.gov/pubmed/36082278
http://dx.doi.org/10.1016/j.jtocrr.2022.100382

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