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Role of 3'-Deoxy-3'-[(18)F] Fluorothymidine Positron Emission Tomography-Computed Tomography as a Predictive Biomarker in Argininosuccinate Synthetase 1-Deficient Thoracic Cancers Treated With Pegargiminase
INTRODUCTION: Pegargiminase (ADI-PEG 20I) degrades arginine in patients with argininosuccinate synthetase 1-deficient malignant pleural mesothelioma (MPM) and NSCLC. Imaging with proliferation biomarker 3'-deoxy-3'-[(18)F] fluorothymidine ((18)F-FLT) positron emission tomography (PET)-comp...
Autores principales: | Szyszko, Teresa A., Dunn, Joel T., Phillips, Melissa M., Bomalaski, John, Sheaff, Michael T., Ellis, Steve, Pike, Lucy, Goh, Vicky, Cook, Gary J.R., Szlosarek, Peter W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445378/ https://www.ncbi.nlm.nih.gov/pubmed/36082278 http://dx.doi.org/10.1016/j.jtocrr.2022.100382 |
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