MINocyclinE to Reduce inflammation and blood brain barrier leakage in small Vessel diseAse (MINERVA) trial study protocol

BACKGROUND: Cerebral small vessel disease (SVD) is a common cause of stroke and cognitive impairment. Recent data has implicated neuroinflammation and increased blood-brain barrier (BBB) permeability in its pathogenesis, but whether such processes are causal and can be therapeutically modified is un...

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Detalles Bibliográficos
Autores principales: Brown, Robin B, Tozer, Daniel J, Loubière, Laurence, Hong, Young T, Fryer, Tim D, Williams, Guy B, Graves, Martin J, Aigbirhio, Franklin I, O’Brien, John T, Markus, Hugh S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Study Protocols
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445404/
https://www.ncbi.nlm.nih.gov/pubmed/36082255
http://dx.doi.org/10.1177/23969873221100338

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