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The association of cesarean section with overweight and neurodevelopment of Chinese children aged 1–5 months

OBJECTIVE: The purpose of this survey was to explore the association of delivery mode with overweight and neurodevelopment of Chinese infants aged 1–5 months. MATERIALS AND METHODS: This study was based on a cross-sectional survey. Data for this study were obtained from the Children’s Nutrition and...

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Autores principales: Zheng, Xiaoguo, Li, Ruili, Wang, Lihong, Yang, Huimin, Li, Linlin, Cui, Jiayin, Zhao, Wenhua, Yang, Zhenyu, Zhang, Qian, Xu, Tao, Wang, Yuying, Chen, Bowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445438/
https://www.ncbi.nlm.nih.gov/pubmed/36081630
http://dx.doi.org/10.3389/fped.2022.940422
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author Zheng, Xiaoguo
Li, Ruili
Wang, Lihong
Yang, Huimin
Li, Linlin
Cui, Jiayin
Zhao, Wenhua
Yang, Zhenyu
Zhang, Qian
Xu, Tao
Wang, Yuying
Chen, Bowen
author_facet Zheng, Xiaoguo
Li, Ruili
Wang, Lihong
Yang, Huimin
Li, Linlin
Cui, Jiayin
Zhao, Wenhua
Yang, Zhenyu
Zhang, Qian
Xu, Tao
Wang, Yuying
Chen, Bowen
author_sort Zheng, Xiaoguo
collection PubMed
description OBJECTIVE: The purpose of this survey was to explore the association of delivery mode with overweight and neurodevelopment of Chinese infants aged 1–5 months. MATERIALS AND METHODS: This study was based on a cross-sectional survey. Data for this study were obtained from the Children’s Nutrition and Health System Survey in China which was conducted from 2019 to 2020. Characteristics of parents and children and the delivery mode were obtained using interview-administered questionnaires. Body mass index-for age z-score (BMI z) was calculated using World Health Organization (WHO) child growth standards. Children’s neurodevelopment was assessed by a trained child health care physician using the Child Psychological Development Scale. The association of delivery mode with infant overweight was analyzed using a multivariable logistic regression model. We conducted a multivariable linear regression model to explore the relationship between delivery modes with neurodevelopment. RESULTS: In total, the present analysis included 1,347 children aged 1–5 months, 35.61% were born via cesarean section, of which 15.21% were overweight. After adjustment for infant characteristics and parental factors, the cesarean section was significantly related with the likehood of being overweight [OR = 1.95; 95% confidence interval (CI): 1.27 to 2.98]. Children born via cesarean section had a 3.41-point decrease in gross motor development (β = −3.41; 95% CI: −5.77 to −1.05), a 3.65-point decrease in fine motor development (β = −3.65; 95% CI: −6.03 to −1.28), and a 2.96-point in language development (β = −2.96; 95% CI: −5.20 to −0.73), a 1.65-point in total development (β = −1.65; 95% CI: −3.17 to −0.14) compared with those who were vaginal birth. CONCLUSION: In our study population, cesarean section was associated with overweight and neurodevelopment outcomes. The cesarean section might increase the likehood of infant overweight, and might decrease the developmental scores of gross motor, fine motor and language. Further studies should be conducted to verify the associations and explore the possible mechanisms.
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spelling pubmed-94454382022-09-07 The association of cesarean section with overweight and neurodevelopment of Chinese children aged 1–5 months Zheng, Xiaoguo Li, Ruili Wang, Lihong Yang, Huimin Li, Linlin Cui, Jiayin Zhao, Wenhua Yang, Zhenyu Zhang, Qian Xu, Tao Wang, Yuying Chen, Bowen Front Pediatr Pediatrics OBJECTIVE: The purpose of this survey was to explore the association of delivery mode with overweight and neurodevelopment of Chinese infants aged 1–5 months. MATERIALS AND METHODS: This study was based on a cross-sectional survey. Data for this study were obtained from the Children’s Nutrition and Health System Survey in China which was conducted from 2019 to 2020. Characteristics of parents and children and the delivery mode were obtained using interview-administered questionnaires. Body mass index-for age z-score (BMI z) was calculated using World Health Organization (WHO) child growth standards. Children’s neurodevelopment was assessed by a trained child health care physician using the Child Psychological Development Scale. The association of delivery mode with infant overweight was analyzed using a multivariable logistic regression model. We conducted a multivariable linear regression model to explore the relationship between delivery modes with neurodevelopment. RESULTS: In total, the present analysis included 1,347 children aged 1–5 months, 35.61% were born via cesarean section, of which 15.21% were overweight. After adjustment for infant characteristics and parental factors, the cesarean section was significantly related with the likehood of being overweight [OR = 1.95; 95% confidence interval (CI): 1.27 to 2.98]. Children born via cesarean section had a 3.41-point decrease in gross motor development (β = −3.41; 95% CI: −5.77 to −1.05), a 3.65-point decrease in fine motor development (β = −3.65; 95% CI: −6.03 to −1.28), and a 2.96-point in language development (β = −2.96; 95% CI: −5.20 to −0.73), a 1.65-point in total development (β = −1.65; 95% CI: −3.17 to −0.14) compared with those who were vaginal birth. CONCLUSION: In our study population, cesarean section was associated with overweight and neurodevelopment outcomes. The cesarean section might increase the likehood of infant overweight, and might decrease the developmental scores of gross motor, fine motor and language. Further studies should be conducted to verify the associations and explore the possible mechanisms. Frontiers Media S.A. 2022-08-23 /pmc/articles/PMC9445438/ /pubmed/36081630 http://dx.doi.org/10.3389/fped.2022.940422 Text en Copyright © 2022 Zheng, Li, Wang, Yang, Li, Cui, Zhao, Yang, Zhang, Xu, Wang and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Zheng, Xiaoguo
Li, Ruili
Wang, Lihong
Yang, Huimin
Li, Linlin
Cui, Jiayin
Zhao, Wenhua
Yang, Zhenyu
Zhang, Qian
Xu, Tao
Wang, Yuying
Chen, Bowen
The association of cesarean section with overweight and neurodevelopment of Chinese children aged 1–5 months
title The association of cesarean section with overweight and neurodevelopment of Chinese children aged 1–5 months
title_full The association of cesarean section with overweight and neurodevelopment of Chinese children aged 1–5 months
title_fullStr The association of cesarean section with overweight and neurodevelopment of Chinese children aged 1–5 months
title_full_unstemmed The association of cesarean section with overweight and neurodevelopment of Chinese children aged 1–5 months
title_short The association of cesarean section with overweight and neurodevelopment of Chinese children aged 1–5 months
title_sort association of cesarean section with overweight and neurodevelopment of chinese children aged 1–5 months
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445438/
https://www.ncbi.nlm.nih.gov/pubmed/36081630
http://dx.doi.org/10.3389/fped.2022.940422
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