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Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review
OBJECTIVE: The aim of this systematic review is to analyse existing evidence on prevalence, patterns, determinants, and healthcare challenges of communicable and non-communicable disease multimorbidity in low- and middle-income countries (LMICs). METHODS: PubMed, Cochrane, and Embase databases were...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445468/ https://www.ncbi.nlm.nih.gov/pubmed/36081708 http://dx.doi.org/10.1177/26335565221112593 |
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author | Kaluvu, Lucy Asogwa, Ogechukwu Augustina Marzà-Florensa, Anna Kyobutungi, Catherine Levitt, Naomi S Boateng, Daniel Klipstein-Grobusch, Kerstin |
author_facet | Kaluvu, Lucy Asogwa, Ogechukwu Augustina Marzà-Florensa, Anna Kyobutungi, Catherine Levitt, Naomi S Boateng, Daniel Klipstein-Grobusch, Kerstin |
author_sort | Kaluvu, Lucy |
collection | PubMed |
description | OBJECTIVE: The aim of this systematic review is to analyse existing evidence on prevalence, patterns, determinants, and healthcare challenges of communicable and non-communicable disease multimorbidity in low- and middle-income countries (LMICs). METHODS: PubMed, Cochrane, and Embase databases were searched from 1(st) January 2000 to 31(st) July 2020. The National Institute of Health (NIH) quality assessment tool was used to critically appraise studies. Findings were summarized in a narrative synthesis. The review was registered with PROSPERO (CRD42019133453). RESULTS: Of 3718 articles screened, 79 articles underwent a full text review of which 11 were included for narrative synthesis. Studies reported on 4 to 20 chronic communicable and non-communicable diseases; prevalence of multimorbidity ranged from 13% in a study conducted among 242,952 participants from 48 LMICS to 87% in a study conducted among 491 participants in South Africa. Multimorbidity was positively associated with older age, female sex, unemployment, and physical inactivity. Significantly higher odds of multimorbidity were noted among obese participants (OR 2.33; 95% CI: 2.19–2.48) and those who consumed alcohol (OR 1.44; 95% CI: 1.25–1.66). The most frequently occurring dyads and triads were HIV and hypertension (23.3%) and HIV, hypertension, and diabetes (63%), respectively. Women and participants from low wealth quintiles reported higher utilization of public healthcare facilities. CONCLUSION: The identification and prevention of risk factors and addressing evidence gaps in multimorbidity clustering is crucial to address the increasing communicable and non-communicable disease multimorbidity in LMICs. To identify communicable and non-communicable diseases trends over time and identify causal relationships, longitudinal studies are warranted. |
format | Online Article Text |
id | pubmed-9445468 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-94454682022-09-07 Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review Kaluvu, Lucy Asogwa, Ogechukwu Augustina Marzà-Florensa, Anna Kyobutungi, Catherine Levitt, Naomi S Boateng, Daniel Klipstein-Grobusch, Kerstin J Multimorb Comorb Review Article OBJECTIVE: The aim of this systematic review is to analyse existing evidence on prevalence, patterns, determinants, and healthcare challenges of communicable and non-communicable disease multimorbidity in low- and middle-income countries (LMICs). METHODS: PubMed, Cochrane, and Embase databases were searched from 1(st) January 2000 to 31(st) July 2020. The National Institute of Health (NIH) quality assessment tool was used to critically appraise studies. Findings were summarized in a narrative synthesis. The review was registered with PROSPERO (CRD42019133453). RESULTS: Of 3718 articles screened, 79 articles underwent a full text review of which 11 were included for narrative synthesis. Studies reported on 4 to 20 chronic communicable and non-communicable diseases; prevalence of multimorbidity ranged from 13% in a study conducted among 242,952 participants from 48 LMICS to 87% in a study conducted among 491 participants in South Africa. Multimorbidity was positively associated with older age, female sex, unemployment, and physical inactivity. Significantly higher odds of multimorbidity were noted among obese participants (OR 2.33; 95% CI: 2.19–2.48) and those who consumed alcohol (OR 1.44; 95% CI: 1.25–1.66). The most frequently occurring dyads and triads were HIV and hypertension (23.3%) and HIV, hypertension, and diabetes (63%), respectively. Women and participants from low wealth quintiles reported higher utilization of public healthcare facilities. CONCLUSION: The identification and prevention of risk factors and addressing evidence gaps in multimorbidity clustering is crucial to address the increasing communicable and non-communicable disease multimorbidity in LMICs. To identify communicable and non-communicable diseases trends over time and identify causal relationships, longitudinal studies are warranted. SAGE Publications 2022-09-01 /pmc/articles/PMC9445468/ /pubmed/36081708 http://dx.doi.org/10.1177/26335565221112593 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Article Kaluvu, Lucy Asogwa, Ogechukwu Augustina Marzà-Florensa, Anna Kyobutungi, Catherine Levitt, Naomi S Boateng, Daniel Klipstein-Grobusch, Kerstin Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review |
title | Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review |
title_full | Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review |
title_fullStr | Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review |
title_full_unstemmed | Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review |
title_short | Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review |
title_sort | multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: a systematic review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445468/ https://www.ncbi.nlm.nih.gov/pubmed/36081708 http://dx.doi.org/10.1177/26335565221112593 |
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