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Aptamer-siRNA chimera and gold nanoparticle modified collagen membrane for the treatment of malignant pleural effusion

Malignant pleural effusion is one of the most common complications of advanced lung cancer and there is no effective clinical treatment at present. Here, we constructed an aptamer-siRNA chimeras/PEI/PEG/gold nanoparticle (AuNP)/collagen membrane that can progressively activate T cells by layer by la...

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Detalles Bibliográficos
Autores principales:	Chen, Wen, Guo, Fengjie, Ren, Zhipeng, Wang, Linghui, Li, Tinghui, Hou, Xiaobin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445489/ https://www.ncbi.nlm.nih.gov/pubmed/36082168 http://dx.doi.org/10.3389/fbioe.2022.973892

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