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Assessing Long-Term Neurodevelopment among Children with Non-Syndromic Single Suture Craniosynostosis

BACKGROUND: Single suture craniosynostosis (SSC) is a disorder, affecting brain growth. Reviewing literature reveals controversialists of papers in this field. METHODS: This prospective study was conducted from 2014 to 2016. All the individuals, aged 2 to 16 years, whose medical records files were c...

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Autores principales: Kalantar-Hormozi, Abdoljalil, Abbaszadeh-Kasbi, Ali, Kalantar-Hormozi, Hadis, Davai, Nazanin Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society for Plastic Surgeons 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446125/
https://www.ncbi.nlm.nih.gov/pubmed/36117890
http://dx.doi.org/10.52547/wjps.11.2.57
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author Kalantar-Hormozi, Abdoljalil
Abbaszadeh-Kasbi, Ali
Kalantar-Hormozi, Hadis
Davai, Nazanin Rita
author_facet Kalantar-Hormozi, Abdoljalil
Abbaszadeh-Kasbi, Ali
Kalantar-Hormozi, Hadis
Davai, Nazanin Rita
author_sort Kalantar-Hormozi, Abdoljalil
collection PubMed
description BACKGROUND: Single suture craniosynostosis (SSC) is a disorder, affecting brain growth. Reviewing literature reveals controversialists of papers in this field. METHODS: This prospective study was conducted from 2014 to 2016. All the individuals, aged 2 to 16 years, whose medical records files were complete, with SSC from 1999 to 2013 were included. All patients had undergone cranial vault remodeling at Mofid Hospital, Tehran, Iran. Wechsler questionnaires, WPPSI-III and WISC-IV, were completed for each child based on his/her age. RESULTS: Seventy children were included, with the mean age of 6.7 (±2.9) years. Forty-six (65.7%) children were boys while 24 (34.3%) were girls. Mean FSIQ for all of children was 95.5 (±13.2). Mean verbal IQ, performance IQ, verbal comprehension, perceptual reasoning, processing speed, and working memory are 93.4 (±14.1), 96.1 (±13.3), 97.5 (±13.9), 102.2 (±12.5), 94.5 (±9.8), and 97.5 (±12.9), respectively. There was statistically significant difference between FSIQ of children with SSC and that of unaffected children (P-value<0.05). There was significant difference between verbal IQ of children with SSC and that of unaffected ones (P-value< 0.007). There was significant difference between in processing speed between affected children and unaffected children (P-value<0.012). CONCLUSION: Children, aged 2 to 6 years, with SSC had a significantly lower Verbal IQ, and children, aged 6 to 16 years, with SSC had a significantly lower processing speed than their healthy counterparts. Though FSIQ of children with SSC falls within normal range, it is a little lower than healthy peers.
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spelling pubmed-94461252022-09-16 Assessing Long-Term Neurodevelopment among Children with Non-Syndromic Single Suture Craniosynostosis Kalantar-Hormozi, Abdoljalil Abbaszadeh-Kasbi, Ali Kalantar-Hormozi, Hadis Davai, Nazanin Rita World J Plast Surg Original Article BACKGROUND: Single suture craniosynostosis (SSC) is a disorder, affecting brain growth. Reviewing literature reveals controversialists of papers in this field. METHODS: This prospective study was conducted from 2014 to 2016. All the individuals, aged 2 to 16 years, whose medical records files were complete, with SSC from 1999 to 2013 were included. All patients had undergone cranial vault remodeling at Mofid Hospital, Tehran, Iran. Wechsler questionnaires, WPPSI-III and WISC-IV, were completed for each child based on his/her age. RESULTS: Seventy children were included, with the mean age of 6.7 (±2.9) years. Forty-six (65.7%) children were boys while 24 (34.3%) were girls. Mean FSIQ for all of children was 95.5 (±13.2). Mean verbal IQ, performance IQ, verbal comprehension, perceptual reasoning, processing speed, and working memory are 93.4 (±14.1), 96.1 (±13.3), 97.5 (±13.9), 102.2 (±12.5), 94.5 (±9.8), and 97.5 (±12.9), respectively. There was statistically significant difference between FSIQ of children with SSC and that of unaffected children (P-value<0.05). There was significant difference between verbal IQ of children with SSC and that of unaffected ones (P-value< 0.007). There was significant difference between in processing speed between affected children and unaffected children (P-value<0.012). CONCLUSION: Children, aged 2 to 6 years, with SSC had a significantly lower Verbal IQ, and children, aged 6 to 16 years, with SSC had a significantly lower processing speed than their healthy counterparts. Though FSIQ of children with SSC falls within normal range, it is a little lower than healthy peers. Iranian Society for Plastic Surgeons 2022-07 /pmc/articles/PMC9446125/ /pubmed/36117890 http://dx.doi.org/10.52547/wjps.11.2.57 Text en https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.(https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Original Article
Kalantar-Hormozi, Abdoljalil
Abbaszadeh-Kasbi, Ali
Kalantar-Hormozi, Hadis
Davai, Nazanin Rita
Assessing Long-Term Neurodevelopment among Children with Non-Syndromic Single Suture Craniosynostosis
title Assessing Long-Term Neurodevelopment among Children with Non-Syndromic Single Suture Craniosynostosis
title_full Assessing Long-Term Neurodevelopment among Children with Non-Syndromic Single Suture Craniosynostosis
title_fullStr Assessing Long-Term Neurodevelopment among Children with Non-Syndromic Single Suture Craniosynostosis
title_full_unstemmed Assessing Long-Term Neurodevelopment among Children with Non-Syndromic Single Suture Craniosynostosis
title_short Assessing Long-Term Neurodevelopment among Children with Non-Syndromic Single Suture Craniosynostosis
title_sort assessing long-term neurodevelopment among children with non-syndromic single suture craniosynostosis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446125/
https://www.ncbi.nlm.nih.gov/pubmed/36117890
http://dx.doi.org/10.52547/wjps.11.2.57
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