Potential role of HTLV-1 Tax-specific cytotoxic t lymphocytes expressing a unique t-cell receptor to promote inflammation of the central nervous system in myelopathy associated with HTLV-1

Human T-lymphotropic virus 1 (HTLV-1) infection causes two serious diseases: adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy (HAM). Immunological studies have revealed that HTLV-1 Tax-specific CD8(+) cytotoxic T-cells (Tax-CTLs) in asymptomatic carriers (ACs) and ATL patients p...

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Detalles Bibliográficos
Autores principales: Tanaka, Yukie, Sato, Tomoo, Yagishita, Naoko, Yamauchi, Junji, Araya, Natsumi, Aratani, Satoko, Takahashi, Katsunori, Kunitomo, Yasuo, Nagasaka, Misako, Kanda, Yoshinobu, Uchimaru, Kaoru, Morio, Tomohiro, Yamano, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446235/
https://www.ncbi.nlm.nih.gov/pubmed/36081501
http://dx.doi.org/10.3389/fimmu.2022.993025

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