Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics

BACKGROUND: Lower respiratory tract infections (LRTI) are a leading cause of critical illness and mortality in mechanically ventilated children; however, the pathogenic microbes frequently remain unknown. We combined traditional diagnostics with metagenomic next generation sequencing (mNGS) to evalu...

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Detalles Bibliográficos
Autores principales: Tsitsiklis, Alexandra, Osborne, Christina M, Kamm, Jack, Williamson, Kayla, Kalantar, Katrina, Dudas, Gytis, Caldera, Saharai, Lyden, Amy, Tan, Michelle, Neff, Norma, Soesanto, Victoria, Harris, J Kirk, Ambroggio, Lilliam, Maddux, Aline B, Carpenter, Todd C, Reeder, Ron W, Locandro, Chris, Simões, Eric A F, Leroue, Matthew K, Hall, Mark W, Zuppa, Athena F, Carcillo, Joseph, Meert, Kathleen L, Sapru, Anil, Pollack, Murray M, McQuillen, Patrick S, Notterman, Daniel A, Dean, J Michael, Zinter, Matt S, Wagner, Brandie D, DeRisi, Joseph L, Mourani, Peter M, Langelier, Charles R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446282/
https://www.ncbi.nlm.nih.gov/pubmed/35544065
http://dx.doi.org/10.1016/S2666-5247(21)00304-9

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