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Comparison of colonic stenting and stoma creation as palliative treatment for incurable malignant colonic obstruction

BACKGROUND AND AIM: Self‐expandable metal stent (SEMS) is a favorable therapeutic option for patients with incurable malignant colonic obstruction (MCO). However, their long‐term efficacy and safety compared with those of stoma creation have not been well investigated. This study aimed to compare th...

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Autores principales: Pattarajierapan, Sukit, Manomayangoon, Chatiyaporn, Tipsuwannakul, Panat, Khomvilai, Supakij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446394/
https://www.ncbi.nlm.nih.gov/pubmed/36091319
http://dx.doi.org/10.1002/jgh3.12800
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author Pattarajierapan, Sukit
Manomayangoon, Chatiyaporn
Tipsuwannakul, Panat
Khomvilai, Supakij
author_facet Pattarajierapan, Sukit
Manomayangoon, Chatiyaporn
Tipsuwannakul, Panat
Khomvilai, Supakij
author_sort Pattarajierapan, Sukit
collection PubMed
description BACKGROUND AND AIM: Self‐expandable metal stent (SEMS) is a favorable therapeutic option for patients with incurable malignant colonic obstruction (MCO). However, their long‐term efficacy and safety compared with those of stoma creation have not been well investigated. This study aimed to compare these long‐term outcomes between these two techniques in patients with incurable MCO. METHODS: This retrospective cohort included patients with incurable MCO with SEMS insertion (n = 105) and stoma creation (n = 97) between January 2009 and December 2019. The primary outcomes were patency after the procedure and 1‐year re‐intervention rates. RESULTS: The patency of the SEMS group was lower than that of the stoma group (88.9 vs 93.2% at 6 months, 84.1 vs 90.5% at 12 months, and 65.8 vs 90.5% at 18 months; log‐rank test, P = 0.024), but 1‐year re‐intervention rates were not different between the groups (10 vs 8%, P = 0.558). The median patency durations were 190 days for SEMS insertion and 231 days for stoma creation. Majority (84%) of SEMS patients did not require any re‐intervention until death. The early complication rate did not differ between the groups (P = 0.377), but SEMS insertion had fewer late minor complications than stoma creation (5 vs 22%, P = 0.001). CONCLUSION: SEMS insertion is a safe and effective treatment for patients with incurable MCO. Although SEMS insertion had a lower patency than stoma creation, especially after 1 year, the 1‐year re‐intervention rates were not different, and SEMS durability was sufficient in most patients.
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spelling pubmed-94463942022-09-09 Comparison of colonic stenting and stoma creation as palliative treatment for incurable malignant colonic obstruction Pattarajierapan, Sukit Manomayangoon, Chatiyaporn Tipsuwannakul, Panat Khomvilai, Supakij JGH Open Original Articles BACKGROUND AND AIM: Self‐expandable metal stent (SEMS) is a favorable therapeutic option for patients with incurable malignant colonic obstruction (MCO). However, their long‐term efficacy and safety compared with those of stoma creation have not been well investigated. This study aimed to compare these long‐term outcomes between these two techniques in patients with incurable MCO. METHODS: This retrospective cohort included patients with incurable MCO with SEMS insertion (n = 105) and stoma creation (n = 97) between January 2009 and December 2019. The primary outcomes were patency after the procedure and 1‐year re‐intervention rates. RESULTS: The patency of the SEMS group was lower than that of the stoma group (88.9 vs 93.2% at 6 months, 84.1 vs 90.5% at 12 months, and 65.8 vs 90.5% at 18 months; log‐rank test, P = 0.024), but 1‐year re‐intervention rates were not different between the groups (10 vs 8%, P = 0.558). The median patency durations were 190 days for SEMS insertion and 231 days for stoma creation. Majority (84%) of SEMS patients did not require any re‐intervention until death. The early complication rate did not differ between the groups (P = 0.377), but SEMS insertion had fewer late minor complications than stoma creation (5 vs 22%, P = 0.001). CONCLUSION: SEMS insertion is a safe and effective treatment for patients with incurable MCO. Although SEMS insertion had a lower patency than stoma creation, especially after 1 year, the 1‐year re‐intervention rates were not different, and SEMS durability was sufficient in most patients. Wiley Publishing Asia Pty Ltd 2022-08-01 /pmc/articles/PMC9446394/ /pubmed/36091319 http://dx.doi.org/10.1002/jgh3.12800 Text en © 2022 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Pattarajierapan, Sukit
Manomayangoon, Chatiyaporn
Tipsuwannakul, Panat
Khomvilai, Supakij
Comparison of colonic stenting and stoma creation as palliative treatment for incurable malignant colonic obstruction
title Comparison of colonic stenting and stoma creation as palliative treatment for incurable malignant colonic obstruction
title_full Comparison of colonic stenting and stoma creation as palliative treatment for incurable malignant colonic obstruction
title_fullStr Comparison of colonic stenting and stoma creation as palliative treatment for incurable malignant colonic obstruction
title_full_unstemmed Comparison of colonic stenting and stoma creation as palliative treatment for incurable malignant colonic obstruction
title_short Comparison of colonic stenting and stoma creation as palliative treatment for incurable malignant colonic obstruction
title_sort comparison of colonic stenting and stoma creation as palliative treatment for incurable malignant colonic obstruction
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446394/
https://www.ncbi.nlm.nih.gov/pubmed/36091319
http://dx.doi.org/10.1002/jgh3.12800
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