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STK25 inhibits PKA signaling by phosphorylating PRKAR1A

In the heart, protein kinase A (PKA) is critical for activating calcium handling and sarcomeric proteins in response to beta-adrenergic stimulation leading to increased myocardial contractility and performance. The catalytic activity of PKA is tightly regulated by regulatory subunits that inhibit th...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaokan, Wang, Bryan Z., Kim, Michael, Nash, Trevor R., Liu, Bohao, Rao, Jenny, Lock, Roberta, Tamargo, Manuel, Soni, Rajesh Kumar, Belov, John, Li, Eric, Vunjak-Novakovic, Gordana, Fine, Barry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446420/ https://www.ncbi.nlm.nih.gov/pubmed/35977512 http://dx.doi.org/10.1016/j.celrep.2022.111203

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