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Optimizing a Bayesian hierarchical adaptive platform trial design for stroke patients
BACKGROUND: Platform trials are well-known for their ability to investigate multiple arms on heterogeneous patient populations and their flexibility to add/drop treatment arms due to efficacy/lack of efficacy. Because of their complexity, it is important to develop highly optimized, transparent, and...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446515/ https://www.ncbi.nlm.nih.gov/pubmed/36068547 http://dx.doi.org/10.1186/s13063-022-06664-4 |