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Knockdown of FOXA1 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the ERK1/2 signalling pathway

BACKGROUND: The available therapeutic options for large bone defects remain extremely limited, requiring new strategies to accelerate bone healing. Genetically modified bone mesenchymal stem cells (BMSCs) with enhanced osteogenic capacity are recognised as one of the most promising treatments for bo...

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Detalles Bibliográficos
Autores principales:	Li, Lijun, Wang, Yibo, Wang, Zhongxiang, Xue, Deting, Dai, Chengxin, Gao, Xiang, Ma, Jianfei, Hang, Kai, Pan, Zhijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446550/ https://www.ncbi.nlm.nih.gov/pubmed/36064451 http://dx.doi.org/10.1186/s13287-022-03133-2

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