Identification of HBEGF+ fibroblasts in the remission of rheumatoid arthritis by integrating single-cell RNA sequencing datasets and bulk RNA sequencing datasets

BACKGROUND: Fibroblasts are important structural cells in synovium and play key roles in maintaining the synovial homeostasis. By single-cell RNA sequencing (scRNA-seq), subpopulation of synovium-resident cells has been reported to protect intra-articular structures from chronic inflammation and pro...

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Detalles Bibliográficos
Autores principales: Chen, Nachun, Fan, Baoying, He, Zhiyong, Yu, Xinping, Wang, Jinjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446562/
https://www.ncbi.nlm.nih.gov/pubmed/36068607
http://dx.doi.org/10.1186/s13075-022-02902-x

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