Cargando…

The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study

BACKGROUND: Triggering receptor expressed on myeloid cell 1 (Trem1) is an important regulator of cellular inflammatory responses. Neuroinflammation is a common thread across various neurological diseases. Soluble Trem1 (sTrem1) in plasma is associated with the development of central nervous system d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Xiaolei, Wei, Tao, Hu, Yachun, Wang, Meng, Tang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446564/ https://www.ncbi.nlm.nih.gov/pubmed/36068612 http://dx.doi.org/10.1186/s12974-022-02582-z

Ejemplares similares

CSF sTREM2 in neurological diseases: a two-sample Mendelian randomization study
por: Dong, Ming-Hao, et al.
Publicado: (2022)

Identifying Suitable Targets for Alzheimer’s Disease and Other Eight Common Neurological Disorders Using the Human Plasma Proteome: A Mendelian Randomization Study
por: Wei, Tao, et al.
Publicado: (2023)

Soluble TREM2: Innocent bystander or active player in neurological diseases?
por: Filipello, Fabia, et al.
Publicado: (2022)

Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant carriers
por: Ashton, Nicholas J., et al.
Publicado: (2019)

Role of TREM-1 in pulmonary tuberculosis patients- analysis of serum soluble TREM-1 levels
por: Feng, Jia-Yih, et al.
Publicado: (2018)

Association of rs2062323 in the TREM1 gene with Alzheimer's disease and cerebrospinal fluid‐soluble TREM2
por: Wang, Zuo‐Teng, et al.
Publicado: (2023)

TREM2 ectodomain and its soluble form in Alzheimer’s disease
por: Yang, Jiaolong, et al.
Publicado: (2020)

In familial Mediterranean fever, soluble TREM-1 plasma level is higher in case of amyloidosis
por: Gorlier, Clémence, et al.
Publicado: (2019)

In Familial Mediterranean Fever, soluble TREM-1 plasma level is higher in case of amyloidosis
por: Ugurlu, Serdal, et al.
Publicado: (2020)

Soluble TREM-1 plasma concentration predicts poor outcome in COVID-19 patients
por: Gibot, Sébastien, et al.
Publicado: (2023)

Cerebrospinal fluid soluble TREM2 in aging and Alzheimer’s disease
por: Henjum, Kristi, et al.
Publicado: (2016)

Does Soluble TREM2 Protect Against Alzheimer's Disease?
por: Brown, Guy C., et al.
Publicado: (2022)

The Role of TREM2 in Alzheimer’s Disease and Other Neurological Disorders
por: Yaghmoor, Faris, et al.
Publicado: (2014)

Association between Cerebrospinal Fluid Soluble TREM2, Alzheimer’s Disease and Other Neurodegenerative Diseases
por: Zhou, Wenchuan, et al.
Publicado: (2023)

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease
por: Heslegrave, Amanda, et al.
Publicado: (2016)

The Emerging Roles and Therapeutic Potential of Soluble TREM2 in Alzheimer’s Disease
por: Zhong, Li, et al.
Publicado: (2019)

The relationship of soluble TREM2 to other biomarkers of sporadic Alzheimer’s disease
por: Park, So-Hee, et al.
Publicado: (2021)

TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation
por: Moutinho, Miguel, et al.
Publicado: (2023)

Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology
por: Qiao, Wenhui, et al.
Publicado: (2023)

The association between cerebrospinal ferritin and soluble triggering receptor expressed on myeloid cells 2 along Alzheimer's continuum
por: Shi, Xiaolei, et al.
Publicado: (2022)

Function of TREM1 and TREM2 in Liver-Related Diseases
por: Sun, Huifang, et al.
Publicado: (2020)

Correction: Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology
por: Qiao, Wenhui, et al.
Publicado: (2023)

Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer’s disease
por: Zhang, Xingyu, et al.
Publicado: (2023)

Increased CSF Soluble TREM2 Concentration in Patients With Neurosyphilis
por: Li, Wurong, et al.
Publicado: (2020)

Genome-Wide Association Studies for Cerebrospinal Fluid Soluble TREM2 in Alzheimer’s Disease
por: Liu, Changan, et al.
Publicado: (2019)

Soluble TREM2 induces inflammatory responses and enhances microglial survival
por: Zhong, Li, et al.
Publicado: (2017)

The Specific Mechanism of TREM2 Regulation of Synaptic Clearance in Alzheimer’s Disease
por: Qin, Qi, et al.
Publicado: (2022)

Soluble TREM2 is a potential biomarker for the severity of primary angiitis of the CNS
por: Guo, Tianshu, et al.
Publicado: (2022)

TREM-1, TREM-2 and their association with disease severity in patients with COVID-19
por: Fan, Ruyue, et al.
Publicado: (2023)

Examining the Causal Inference of Leptin and Soluble Plasma Leptin Receptor Levels on Schizophrenia: A Mendelian Randomization Study
por: Chen, Guoqing, et al.
Publicado: (2021)

Mendelian randomization to evaluate the effect of plasma vitamin C levels on the risk of Alzheimer’s disease
por: Liu, Haijie, et al.
Publicado: (2021)

Causal relationship between gastroesophageal reflux disease, Barrett's esophagus, and epilepsy: A bidirectional Mendelian randomization study
por: Liu, Xiaoduo, et al.
Publicado: (2023)

Mendelian randomization supports causality between overweight status and accelerated aging
por: Chen, Zong, et al.
Publicado: (2023)

Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer’s disease model
por: Zhong, Li, et al.
Publicado: (2019)

Soluble TREM2 levels associate with conversion from mild cognitive impairment to Alzheimer’s disease
por: Zhao, Aonan, et al.
Publicado: (2022)

Prognostic Utility of Soluble TREM‐1 in Predicting Mortality and Cardiovascular Events in Patients With Acute Myocardial Infarction
por: Wang, Yun Kai, et al.
Publicado: (2018)

The Prognostic Value of Serum Soluble TREM-1 on Outcome in Adult Patients with Sepsis
por: Kung, Chia-Te, et al.
Publicado: (2021)

A Mendelian Randomization Study of Plasma Homocysteine and Multiple Myeloma
por: Xuan, Yang, et al.
Publicado: (2016)

The Association between Blood Lipids and Systemic Lupus Erythematosus: A Two-Sample Mendelian Randomization Research
por: Ding, Yang, et al.
Publicado: (2022)

Plasma C-Reactive Protein and Abdominal Aortic Aneurysm: A Mendelian Randomization Analysis
por: Qin, Xue-Ying, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_nji72bbf58bqj30kllc75p5uds