Hydrogel–metal-organic-framework hybrids mediated efficient oral delivery of siRNA for the treatment of ulcerative colitis

BACKGROUND: Ulcerative colitis (UC) is a major type of inflammatory bowel disease (IBD), which could induce bloody stool, diarrhea, colon atrophy and eventually lead to colorectal cancer. The conventional daily oral administration of drugs only relieve the inflammatory response of colon in the short...

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Detalles Bibliográficos
Autores principales: Gao, Meng, Yang, Chen, Wu, Chenghu, Chen, Yue, Zhuang, Hongqin, Wang, Jilong, Cao, Zhiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446571/
https://www.ncbi.nlm.nih.gov/pubmed/36064365
http://dx.doi.org/10.1186/s12951-022-01603-6

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