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Low-level constitutional mosaicism of BRCA1 in two women with young onset ovarian cancer
Germline pathogenic variants in BRCA1 and BRCA2 cause hereditary breast and ovarian cancer. The vast majority of these variants are inherited from a parent. De novo constitutional pathogenic variants are rare. Even fewer cases of constitutional mosaicism have been reported and these have mostly been...
Главные авторы: | , , , , , , , |
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Формат: | Online Статья Текст |
Язык: | English |
Опубликовано: |
BioMed Central
2022
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Предметы: | |
Online-ссылка: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446595/ https://www.ncbi.nlm.nih.gov/pubmed/36068545 http://dx.doi.org/10.1186/s13053-022-00237-x |