Identification of hACE2-interacting sites in SARS-CoV-2 spike receptor binding domain for antiviral drugs screening

The key structure of the interface between the spike protein of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and human angiotensin-converting enzyme 2 (hACE2) acts as an essential switch for cell entry by the virus and drugs targets. However, this is largely unknown. Here, we tested...

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Detalles Bibliográficos
Autores principales: Hu, Xiaopeng, Cui, Jiahua, Chen, Jun, Du, Shujuan, Wang, Xinyu, Zhang, Yabin, Qian, Jiajun, Chen, Haifeng, Wei, Fang, Cai, Qiliang, Jia, Jinping, Wu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446661/
https://www.ncbi.nlm.nih.gov/pubmed/36084746
http://dx.doi.org/10.1016/j.virusres.2022.198915

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