Intraosseous infusion of acyclovir in a neonate

Intraosseous (IO) access offers a fast and reliable route for administration of fluids and drugs when intravenous (IV) accesses like umbilical, peripheral, or peripherally inserted central lines fail in critically ill neonates. Several medications can be successfully administered via the IO route, h...

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Autores principales: De Marca, Saverio, Calafatti, Matteo, Romaniello, Luciana, Pesce, Simona, Lapolla, Rosa, Gizzi, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446673/
https://www.ncbi.nlm.nih.gov/pubmed/36068631
http://dx.doi.org/10.1186/s13052-022-01353-z
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author De Marca, Saverio
Calafatti, Matteo
Romaniello, Luciana
Pesce, Simona
Lapolla, Rosa
Gizzi, Camilla
author_facet De Marca, Saverio
Calafatti, Matteo
Romaniello, Luciana
Pesce, Simona
Lapolla, Rosa
Gizzi, Camilla
author_sort De Marca, Saverio
collection PubMed
description Intraosseous (IO) access offers a fast and reliable route for administration of fluids and drugs when intravenous (IV) accesses like umbilical, peripheral, or peripherally inserted central lines fail in critically ill neonates. Several medications can be successfully administered via the IO route, however only limited information is available regarding IO administration of antiviral agents. We present the case of a 2-week-old neonate, admitted to the Neonatal Intensive Care Unit (NICU) due to suspected meningitis, who received acyclovir through IO infusion after the venous access was lost and a new one could not be established. No complications were reported within 12 months of follow up. This report highlights the feasibility of IO acyclovir infusion when IV accesses fail in a critically ill neonate.
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spelling pubmed-94466732022-09-07 Intraosseous infusion of acyclovir in a neonate De Marca, Saverio Calafatti, Matteo Romaniello, Luciana Pesce, Simona Lapolla, Rosa Gizzi, Camilla Ital J Pediatr Letter to the Editor Intraosseous (IO) access offers a fast and reliable route for administration of fluids and drugs when intravenous (IV) accesses like umbilical, peripheral, or peripherally inserted central lines fail in critically ill neonates. Several medications can be successfully administered via the IO route, however only limited information is available regarding IO administration of antiviral agents. We present the case of a 2-week-old neonate, admitted to the Neonatal Intensive Care Unit (NICU) due to suspected meningitis, who received acyclovir through IO infusion after the venous access was lost and a new one could not be established. No complications were reported within 12 months of follow up. This report highlights the feasibility of IO acyclovir infusion when IV accesses fail in a critically ill neonate. BioMed Central 2022-09-06 /pmc/articles/PMC9446673/ /pubmed/36068631 http://dx.doi.org/10.1186/s13052-022-01353-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Letter to the Editor
De Marca, Saverio
Calafatti, Matteo
Romaniello, Luciana
Pesce, Simona
Lapolla, Rosa
Gizzi, Camilla
Intraosseous infusion of acyclovir in a neonate
title Intraosseous infusion of acyclovir in a neonate
title_full Intraosseous infusion of acyclovir in a neonate
title_fullStr Intraosseous infusion of acyclovir in a neonate
title_full_unstemmed Intraosseous infusion of acyclovir in a neonate
title_short Intraosseous infusion of acyclovir in a neonate
title_sort intraosseous infusion of acyclovir in a neonate
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446673/
https://www.ncbi.nlm.nih.gov/pubmed/36068631
http://dx.doi.org/10.1186/s13052-022-01353-z
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