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CD47 as a promising therapeutic target in oncology
CD47 is ubiquitously expressed on the surface of cells and plays a critical role in self-recognition. By interacting with SIRPα, TSP-1 and integrins, CD47 modulates cellular phagocytosis by macrophages, determines life span of individual erythrocytes, regulates activation of immune cells, and manipu...
Autores principales: | Zhao, Hai, Song, Shuangshuang, Ma, Junwei, Yan, Zhiyong, Xie, Hongwei, Feng, Ying, Che, Shusheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446754/ https://www.ncbi.nlm.nih.gov/pubmed/36081498 http://dx.doi.org/10.3389/fimmu.2022.757480 |
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