Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study

BACKGROUND: Neuroinflammation is emerging as an important pathological process in frontotemporal dementia (FTD), but biomarkers are lacking. We aimed to determine the value of complement proteins, which are key components of innate immunity, as biomarkers in cerebrospinal fluid (CSF) and plasma of p...

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Detalles Bibliográficos
Autores principales: van der Ende, Emma L., Heller, Carolin, Sogorb-Esteve, Aitana, Swift, Imogen J., McFall, David, Peakman, Georgia, Bouzigues, Arabella, Poos, Jackie M., Jiskoot, Lize C., Panman, Jessica L., Papma, Janne M., Meeter, Lieke H., Dopper, Elise G. P., Bocchetta, Martina, Todd, Emily, Cash, David, Graff, Caroline, Synofzik, Matthis, Moreno, Fermin, Finger, Elizabeth, Sanchez-Valle, Raquel, Vandenberghe, Rik, Laforce, Robert, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B., Butler, Chris, Ducharme, Simon, Gerhard, Alexander, Danek, Adrian, Levin, Johannes, Pijnenburg, Yolande A. L., Otto, Markus, Borroni, Barbara, Tagliavini, Fabrizio, de Mendonça, Alexandre, Santana, Isabel, Galimberti, Daniela, Sorbi, Sandro, Zetterberg, Henrik, Huang, Eric, van Swieten, John C., Rohrer, Jonathan D., Seelaar, Harro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446850/
https://www.ncbi.nlm.nih.gov/pubmed/36064709
http://dx.doi.org/10.1186/s12974-022-02573-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446850/
https://www.ncbi.nlm.nih.gov/pubmed/36064709
http://dx.doi.org/10.1186/s12974-022-02573-0

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