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Tau seeding activity in various regions of down syndrome brain assessed by two novel assays

Propagation of tau pathology via the seeding of naive tau aggregation underlies the progression of Alzheimer’s disease (AD) and related tauopathies. Individuals with Down syndrome (DS) develop tau pathology at the fourth decade of life, but tau seeding activity in DS brain has not yet been determine...

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Detalles Bibliográficos
Autores principales:	Jin, Nana, Gu, Jianlan, Wu, Ruozhen, Chu, Dandan, Tung, Yunn Chyn, Wegiel, Jerzy, Wisniewski, Thomas, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446852/ https://www.ncbi.nlm.nih.gov/pubmed/36064460 http://dx.doi.org/10.1186/s40478-022-01436-2

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