A new flow cytometry assay identifies recipient IgG subtype antibodies binding donor cells: increasing donor availability for highly sensitised patients

OBJECTIVES: There are four immunoglobulin (IgG) subtypes that have varying complement‐activating ability: strong (IgG3 and IgG1) and weak (IgG2 and IgG4). The standard flow cytometric crossmatch (FCM) assay does not distinguish between the various subtypes of the IgG molecule. This study outlines th...

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Detalles Bibliográficos
Autores principales: Rao, Prakash N, Deo, Dayanand D, Gaur, Amitabh, Baran, David A, Zucker, Mark J, Kapoor, Saurabh, Marchioni, Misty A, Almendral, Jesus, Kandula, Praveen, Patel, Anup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446897/
https://www.ncbi.nlm.nih.gov/pubmed/36092480
http://dx.doi.org/10.1002/cti2.1415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446897/
https://www.ncbi.nlm.nih.gov/pubmed/36092480
http://dx.doi.org/10.1002/cti2.1415

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