Abstract 1 Distinctive and Differentiation-State Dependent DNA Damage Response of Hematopoietic Stem Cells to Genotoxic Noxae

INTRODUCTION: Hematopoietic stem cells (HSCs) sustain lifelong blood production and can be used in allogenic stem cell transplantation for treatment of hematological malignancies, yet the mechanisms of their DNA damage response (DDR) remain largely unexplored. Genotoxic damage can be induced by chem...

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Detalles Bibliográficos
Autores principales: Becker, Fabienne, Ouzin, Meryem, Lucks, Luzie, Christ, Kathrin, Liedtke, Stefanie, Kögler, Gesine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Preclinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446908/
http://dx.doi.org/10.1093/stcltm/szac057.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446908/
http://dx.doi.org/10.1093/stcltm/szac057.001

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