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Aging exacerbates the brain inflammatory micro-environment contributing to α-synuclein pathology and functional deficits in a mouse model of DLB/PD

BACKGROUND: Although ɑ-synuclein (ɑ-syn) spreading in age-related neurodegenerative diseases such as Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB) has been extensively investigated, the role of aging in the manifestation of disease remains unclear. METHODS: We explored the role of agi...

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Detalles Bibliográficos
Autores principales:	Iba, Michiyo, McDevitt, Ross A., Kim, Changyoun, Roy, Roshni, Sarantopoulou, Dimitra, Tommer, Ella, Siegars, Byron, Sallin, Michelle, Kwon, Somin, Sen, Jyoti Misra, Sen, Ranjan, Masliah, Eliezer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447339/ https://www.ncbi.nlm.nih.gov/pubmed/36064424 http://dx.doi.org/10.1186/s13024-022-00564-6

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