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CircPRKCH modulates extracellular matrix formation and metabolism by regulating the miR-145/HGF axis in osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a chronic degenerative joint disease. Extracellular matrix (ECM) degradation is essential for OA progression. Previous studies have shown that circular RNAs (circRNAs) are involved in the pathological process of OA. CircPRKCH has been shown to be upregulated in OA...

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Detalles Bibliográficos
Autores principales:	Que, Wenzhong, Liu, Huili, Yang, Qinqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447342/ https://www.ncbi.nlm.nih.gov/pubmed/36068644 http://dx.doi.org/10.1186/s13075-022-02893-9

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