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DMRscaler: a scale-aware method to identify regions of differential DNA methylation spanning basepair to multi-megabase features
BACKGROUND: Pathogenic mutations in genes that control chromatin function have been implicated in rare genetic syndromes. These chromatin modifiers exhibit extraordinary diversity in the scale of the epigenetic changes they affect, from single basepair modifications by DNMT1 to whole genome structur...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447346/ https://www.ncbi.nlm.nih.gov/pubmed/36064314 http://dx.doi.org/10.1186/s12859-022-04899-1 |