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Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis

BACKGROUND: Chlorhexidine (CHX) is not prescribed as a mouthwash for long-term use; therefore, probiotic/herbal mouthwashes are being investigated. This study compared the effect of 3 commercial mouthwashes on plaque index (PI), gingival index (GI), and bleeding index (BI) in patients with chronic g...

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Autores principales: Abullais, Shahabe Saquib, Patel, Sabiha Ilyas, Asiri, Elyas Ali, Jathmi, Adel Ali Ahmed, Alkhayri, Afnan Hassan, Mousa, Yosra Mohammed, Ganem, Atheer Abdulhade, Mattoo, Khurshid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447349/
https://www.ncbi.nlm.nih.gov/pubmed/36050872
http://dx.doi.org/10.12659/MSM.937111
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author Abullais, Shahabe Saquib
Patel, Sabiha Ilyas
Asiri, Elyas Ali
Jathmi, Adel Ali Ahmed
Alkhayri, Afnan Hassan
Mousa, Yosra Mohammed
Ganem, Atheer Abdulhade
Mattoo, Khurshid A.
author_facet Abullais, Shahabe Saquib
Patel, Sabiha Ilyas
Asiri, Elyas Ali
Jathmi, Adel Ali Ahmed
Alkhayri, Afnan Hassan
Mousa, Yosra Mohammed
Ganem, Atheer Abdulhade
Mattoo, Khurshid A.
author_sort Abullais, Shahabe Saquib
collection PubMed
description BACKGROUND: Chlorhexidine (CHX) is not prescribed as a mouthwash for long-term use; therefore, probiotic/herbal mouthwashes are being investigated. This study compared the effect of 3 commercial mouthwashes on plaque index (PI), gingival index (GI), and bleeding index (BI) in patients with chronic gingivitis. MATERIAL/METHODS: Forty-five patients (all with moderate plaque) were randomly allocated into 3 groups (Gp): Gp 1 (CHX), Gp 2 (Manuka), and Gp 3 (Pro-Dental). Three periodontal clinical parameters – PI, GI, and BI – were recorded at baseline and on days 7, 14, and 28. An oral hygiene maintenance program was followed by a double-blinded intervention (coded bottle containing mouthwash). Both inter-group and intra-group comparisons were made using analysis of variance (ANOVA) with multiple t tests. All probable values were considered to have various levels of significance at P<0.05 or below. RESULTS: All indices for all groups showed higher values (mean) at baseline, which were lower on days 7, 14, and 28. No differences in any clinical parameter at any point of time existed between Gp 1 and Gp 2. There were, however, significant differences (P<0.05) between Gp 1/Gp 3 and Gp 2/Gp 3 for all clinical parameters at all observed time periods (days 7, 14, 28). Intra-group comparison for all groups demonstrated highly significant differences between baseline values and other time points. CONCLUSIONS: For managing chronic gingivitis, Manuka mouthwash is as effective as a CHX mouthwash, as there were no differences observed in any clinical parameters at any point points.
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spelling pubmed-94473492022-10-03 Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis Abullais, Shahabe Saquib Patel, Sabiha Ilyas Asiri, Elyas Ali Jathmi, Adel Ali Ahmed Alkhayri, Afnan Hassan Mousa, Yosra Mohammed Ganem, Atheer Abdulhade Mattoo, Khurshid A. Med Sci Monit Clinical Research BACKGROUND: Chlorhexidine (CHX) is not prescribed as a mouthwash for long-term use; therefore, probiotic/herbal mouthwashes are being investigated. This study compared the effect of 3 commercial mouthwashes on plaque index (PI), gingival index (GI), and bleeding index (BI) in patients with chronic gingivitis. MATERIAL/METHODS: Forty-five patients (all with moderate plaque) were randomly allocated into 3 groups (Gp): Gp 1 (CHX), Gp 2 (Manuka), and Gp 3 (Pro-Dental). Three periodontal clinical parameters – PI, GI, and BI – were recorded at baseline and on days 7, 14, and 28. An oral hygiene maintenance program was followed by a double-blinded intervention (coded bottle containing mouthwash). Both inter-group and intra-group comparisons were made using analysis of variance (ANOVA) with multiple t tests. All probable values were considered to have various levels of significance at P<0.05 or below. RESULTS: All indices for all groups showed higher values (mean) at baseline, which were lower on days 7, 14, and 28. No differences in any clinical parameter at any point of time existed between Gp 1 and Gp 2. There were, however, significant differences (P<0.05) between Gp 1/Gp 3 and Gp 2/Gp 3 for all clinical parameters at all observed time periods (days 7, 14, 28). Intra-group comparison for all groups demonstrated highly significant differences between baseline values and other time points. CONCLUSIONS: For managing chronic gingivitis, Manuka mouthwash is as effective as a CHX mouthwash, as there were no differences observed in any clinical parameters at any point points. International Scientific Literature, Inc. 2022-09-02 /pmc/articles/PMC9447349/ /pubmed/36050872 http://dx.doi.org/10.12659/MSM.937111 Text en © Med Sci Monit, 2022 https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Abullais, Shahabe Saquib
Patel, Sabiha Ilyas
Asiri, Elyas Ali
Jathmi, Adel Ali Ahmed
Alkhayri, Afnan Hassan
Mousa, Yosra Mohammed
Ganem, Atheer Abdulhade
Mattoo, Khurshid A.
Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis
title Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis
title_full Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis
title_fullStr Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis
title_full_unstemmed Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis
title_short Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis
title_sort comparative evaluation of 3 commercial mouthwash formulations on clinical parameters of chronic gingivitis
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447349/
https://www.ncbi.nlm.nih.gov/pubmed/36050872
http://dx.doi.org/10.12659/MSM.937111
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