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Oral Selective Estrogen Receptor Degraders (SERDs) in Breast Cancer: Advances, Challenges, and Current Status
Several endocrine therapies are currently available for the treatment of estrogen receptor (ER) positive breast cancer, but the clinical benefit of these agents is limited by endocrine therapy drug resistance. A common mechanism of endocrine therapy resistance is ESR1 mutations. The first-generation...
Autores principales: | Downton, Teesha, Zhou, Fiona, Segara, Davendra, Jeselsohn, Rinath, Lim, Elgene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447452/ https://www.ncbi.nlm.nih.gov/pubmed/36081610 http://dx.doi.org/10.2147/DDDT.S380925 |
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