Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC

Misidentification, cross-contamination and genetic drift of continuous animal cell lines are persistent problems in biomedical research, leading to erroneous results and inconsistent or invalidated studies. The establishment of immortalized hepatic stellate cell line Col-GFP HSC was reported in PLoS...

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Autores principales: Meurer, Steffen K., Brenner, David A., Weiskirchen, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447916/
https://www.ncbi.nlm.nih.gov/pubmed/36067186
http://dx.doi.org/10.1371/journal.pone.0274219
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author Meurer, Steffen K.
Brenner, David A.
Weiskirchen, Ralf
author_facet Meurer, Steffen K.
Brenner, David A.
Weiskirchen, Ralf
author_sort Meurer, Steffen K.
collection PubMed
description Misidentification, cross-contamination and genetic drift of continuous animal cell lines are persistent problems in biomedical research, leading to erroneous results and inconsistent or invalidated studies. The establishment of immortalized hepatic stellate cell line Col-GFP HSC was reported in PLoS One in the year 2013. In the present study a multi loci short tandem repeat signature for this cell line was established that allows for unique cell line authentication.
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spelling pubmed-94479162022-09-07 Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC Meurer, Steffen K. Brenner, David A. Weiskirchen, Ralf PLoS One Research Article Misidentification, cross-contamination and genetic drift of continuous animal cell lines are persistent problems in biomedical research, leading to erroneous results and inconsistent or invalidated studies. The establishment of immortalized hepatic stellate cell line Col-GFP HSC was reported in PLoS One in the year 2013. In the present study a multi loci short tandem repeat signature for this cell line was established that allows for unique cell line authentication. Public Library of Science 2022-09-06 /pmc/articles/PMC9447916/ /pubmed/36067186 http://dx.doi.org/10.1371/journal.pone.0274219 Text en © 2022 Meurer et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Meurer, Steffen K.
Brenner, David A.
Weiskirchen, Ralf
Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC
title Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC
title_full Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC
title_fullStr Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC
title_full_unstemmed Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC
title_short Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC
title_sort multiplex short tandem repeat profiling of immortalized hepatic stellate cell line col-gfp hsc
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447916/
https://www.ncbi.nlm.nih.gov/pubmed/36067186
http://dx.doi.org/10.1371/journal.pone.0274219
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