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COVID-19 rapid molecular point-of-care testing is effective and cost-beneficial for the acute care of trauma patients

PURPOSE: To evaluate the accuracy and cost benefit of a rapid molecular point-of-care testing (POCT) device detecting COVID-19 within a traumatological emergency department. BACKGROUND: Despite continuous withdrawal of COVID-19 restrictions, hospitals will remain particularly vulnerable to local out...

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Autores principales: Stolberg-Stolberg, Josef, Jacob, Elena, Kuehn, Joachim, Hennies, Marc, Hafezi, Wali, Freistuehler, Moritz, Koeppe, Jeanette, Friedrich, Alex W., Katthagen, J. Christoph, Raschke, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447950/
https://www.ncbi.nlm.nih.gov/pubmed/36066585
http://dx.doi.org/10.1007/s00068-022-02091-x
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author Stolberg-Stolberg, Josef
Jacob, Elena
Kuehn, Joachim
Hennies, Marc
Hafezi, Wali
Freistuehler, Moritz
Koeppe, Jeanette
Friedrich, Alex W.
Katthagen, J. Christoph
Raschke, Michael J.
author_facet Stolberg-Stolberg, Josef
Jacob, Elena
Kuehn, Joachim
Hennies, Marc
Hafezi, Wali
Freistuehler, Moritz
Koeppe, Jeanette
Friedrich, Alex W.
Katthagen, J. Christoph
Raschke, Michael J.
author_sort Stolberg-Stolberg, Josef
collection PubMed
description PURPOSE: To evaluate the accuracy and cost benefit of a rapid molecular point-of-care testing (POCT) device detecting COVID-19 within a traumatological emergency department. BACKGROUND: Despite continuous withdrawal of COVID-19 restrictions, hospitals will remain particularly vulnerable to local outbreaks which is reflected by a higher institution-specific basic reproduction rate. Patients admitted to the emergency department with unknown COVID-19 infection status due to a- or oligosymptomatic COVID-19 infection put other patients and health care workers at risk, while fast diagnosis and treatment is necessary. Delayed testing results in additional costs to the health care system. METHODS: From the 8th of April 2021 until 31st of December 2021, all patients admitted to the emergency department were tested with routine RT-PCR and rapid molecular POCT device (Abbott ID NOW™ COVID-19). COVID-19-related additional costs for patients admitted via shock room or emergency department were calculated based on internal cost allocations. RESULTS: 1133 rapid molecular tests resulted in a sensitivity of 83.3% (95% CI 35.9–99.6%), specificity of 99.8% (95% CI 99.4–100%), a positive predictive value of 71.4% (95% CI 29–96.3%) and a negative predictive value of 99.9% (95% CI 99.5–100%) as compared to RT-PCR. Without rapid COVID-19 testing, each emergency department and shock room admission with subsequent surgery showed additional direct costs of 2631.25€, without surgery of 729.01€. CONCLUSION: Although rapid molecular COVID-19 testing can initially be more expensive than RT-PCR, subsequent cost savings, improved workflows and workforce protection outweigh this effect by far. The data of this study support the use of a rapid molecular POCT device in a traumatological emergency department.
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spelling pubmed-94479502022-09-06 COVID-19 rapid molecular point-of-care testing is effective and cost-beneficial for the acute care of trauma patients Stolberg-Stolberg, Josef Jacob, Elena Kuehn, Joachim Hennies, Marc Hafezi, Wali Freistuehler, Moritz Koeppe, Jeanette Friedrich, Alex W. Katthagen, J. Christoph Raschke, Michael J. Eur J Trauma Emerg Surg Original Article PURPOSE: To evaluate the accuracy and cost benefit of a rapid molecular point-of-care testing (POCT) device detecting COVID-19 within a traumatological emergency department. BACKGROUND: Despite continuous withdrawal of COVID-19 restrictions, hospitals will remain particularly vulnerable to local outbreaks which is reflected by a higher institution-specific basic reproduction rate. Patients admitted to the emergency department with unknown COVID-19 infection status due to a- or oligosymptomatic COVID-19 infection put other patients and health care workers at risk, while fast diagnosis and treatment is necessary. Delayed testing results in additional costs to the health care system. METHODS: From the 8th of April 2021 until 31st of December 2021, all patients admitted to the emergency department were tested with routine RT-PCR and rapid molecular POCT device (Abbott ID NOW™ COVID-19). COVID-19-related additional costs for patients admitted via shock room or emergency department were calculated based on internal cost allocations. RESULTS: 1133 rapid molecular tests resulted in a sensitivity of 83.3% (95% CI 35.9–99.6%), specificity of 99.8% (95% CI 99.4–100%), a positive predictive value of 71.4% (95% CI 29–96.3%) and a negative predictive value of 99.9% (95% CI 99.5–100%) as compared to RT-PCR. Without rapid COVID-19 testing, each emergency department and shock room admission with subsequent surgery showed additional direct costs of 2631.25€, without surgery of 729.01€. CONCLUSION: Although rapid molecular COVID-19 testing can initially be more expensive than RT-PCR, subsequent cost savings, improved workflows and workforce protection outweigh this effect by far. The data of this study support the use of a rapid molecular POCT device in a traumatological emergency department. Springer Berlin Heidelberg 2022-09-06 2023 /pmc/articles/PMC9447950/ /pubmed/36066585 http://dx.doi.org/10.1007/s00068-022-02091-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Stolberg-Stolberg, Josef
Jacob, Elena
Kuehn, Joachim
Hennies, Marc
Hafezi, Wali
Freistuehler, Moritz
Koeppe, Jeanette
Friedrich, Alex W.
Katthagen, J. Christoph
Raschke, Michael J.
COVID-19 rapid molecular point-of-care testing is effective and cost-beneficial for the acute care of trauma patients
title COVID-19 rapid molecular point-of-care testing is effective and cost-beneficial for the acute care of trauma patients
title_full COVID-19 rapid molecular point-of-care testing is effective and cost-beneficial for the acute care of trauma patients
title_fullStr COVID-19 rapid molecular point-of-care testing is effective and cost-beneficial for the acute care of trauma patients
title_full_unstemmed COVID-19 rapid molecular point-of-care testing is effective and cost-beneficial for the acute care of trauma patients
title_short COVID-19 rapid molecular point-of-care testing is effective and cost-beneficial for the acute care of trauma patients
title_sort covid-19 rapid molecular point-of-care testing is effective and cost-beneficial for the acute care of trauma patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447950/
https://www.ncbi.nlm.nih.gov/pubmed/36066585
http://dx.doi.org/10.1007/s00068-022-02091-x
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