Ulinastatin alleviates early brain injury after intracerebral hemorrhage by inhibiting oxidative stress and neuroinflammation via ROS/MAPK/Nrf2 signaling pathway

PURPOSE: Spontaneous intracerebral hemorrhage (ICH) is still a major public health problem, with high mortality and disability. Ulinastatin (UTI) was purified from human urine and has been reported to be anti-inflammatory, organ protective, and antioxidative stress. However, the neuroprotection of U...

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Detalles Bibliográficos
Autores principales: Wu, Xi, Jiao, Wei, Chen, Junhui, Tao, Yunna, Zhang, Jing, Wang, Yuhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448248/
https://www.ncbi.nlm.nih.gov/pubmed/36074399
http://dx.doi.org/10.1590/acb370606

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