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Pharmacokinetic improvement provided by microneedle patch in delivering bee venom, a case study in combating scopolamine-induced neurodegeneration in mouse model

Much research has shown Bee venom to be an effective neuroprotective agent. However, the usual transdermal injection of bee venom poses many pharmacokinetic disadvantages. Here, we compared the administration of bee venom via subcutaneous injection (SC) and via Microneedle patch (MN). Both administr...

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Detalles Bibliográficos
Autores principales: Nguyen, Cong Duc, Yoo, Jaehee, An, Eun Jin, Sung, Chang Yub, Jeong, Do Hyeon, Park, Soo-Yeon, Kim, Jae-Hong, Lee, Gihyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448392/
https://www.ncbi.nlm.nih.gov/pubmed/36065088
http://dx.doi.org/10.1080/10717544.2022.2116129