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Pharmacokinetic improvement provided by microneedle patch in delivering bee venom, a case study in combating scopolamine-induced neurodegeneration in mouse model
Much research has shown Bee venom to be an effective neuroprotective agent. However, the usual transdermal injection of bee venom poses many pharmacokinetic disadvantages. Here, we compared the administration of bee venom via subcutaneous injection (SC) and via Microneedle patch (MN). Both administr...
Autores principales: | Nguyen, Cong Duc, Yoo, Jaehee, An, Eun Jin, Sung, Chang Yub, Jeong, Do Hyeon, Park, Soo-Yeon, Kim, Jae-Hong, Lee, Gihyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448392/ https://www.ncbi.nlm.nih.gov/pubmed/36065088 http://dx.doi.org/10.1080/10717544.2022.2116129 |
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