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Estimating the Prevalence of Bladder Cancer by Stage in Iran as a Developing Country
Background: Bladder cancer is among the 10 most common cancers globally and in Iran. The prevalence rate is a crucial metric for both estimating disease burden and policymakers. On the other hand, bladder cancer is a heterogeneous disease with different stages, high recurrence, and progression rate....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iran University of Medical Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448492/ https://www.ncbi.nlm.nih.gov/pubmed/36128281 http://dx.doi.org/10.47176/mjiri.36.37 |
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author | Rashidian, Hamideh Haghdoost, Ali Akbar Daroudi, Rajabali Raadabadi, Mehdi Ebadzadeh, Mohammad Reza Zendehdel, Kazem |
author_facet | Rashidian, Hamideh Haghdoost, Ali Akbar Daroudi, Rajabali Raadabadi, Mehdi Ebadzadeh, Mohammad Reza Zendehdel, Kazem |
author_sort | Rashidian, Hamideh |
collection | PubMed |
description | Background: Bladder cancer is among the 10 most common cancers globally and in Iran. The prevalence rate is a crucial metric for both estimating disease burden and policymakers. On the other hand, bladder cancer is a heterogeneous disease with different stages, high recurrence, and progression rate. In planning treatment procedures, it is important to know the prevalence of bladder cancer by stages. In the current study, we aimed to estimate the 5-year prevalence of bladder cancer by stages using the Markov model. Methods: This was a simulation study. To estimate the 5-year prevalence of bladder cancer by stages, we used the Markov model with a time horizon of 5 years following diagnosis. We simulated the natural history of bladder cancer using a literature review. We extracted survival rate, stage-specific recurrence, and progression rate using local and international publications and expert opinion. In addition, we used the Iranian life table and extracted probabilities of mortality due to other causes of death. Results: Five-year prevalence of bladder cancer for the year 2018 was estimated at 21,807 patients. Non- muscle-invasive bladder cancer accounted for around 68% of all cases, with 42% in the Ta low-grade stage. About 32% of bladder cancer prevalent cases were muscle-invasive bladder cancer patients, from which about 8% had metastatic tumors. Conclusion: Researchers and policymakers can utilize the findings of this study to conduct economic burden analyses and plan resource allocation. |
format | Online Article Text |
id | pubmed-9448492 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Iran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-94484922022-09-19 Estimating the Prevalence of Bladder Cancer by Stage in Iran as a Developing Country Rashidian, Hamideh Haghdoost, Ali Akbar Daroudi, Rajabali Raadabadi, Mehdi Ebadzadeh, Mohammad Reza Zendehdel, Kazem Med J Islam Repub Iran Original Article Background: Bladder cancer is among the 10 most common cancers globally and in Iran. The prevalence rate is a crucial metric for both estimating disease burden and policymakers. On the other hand, bladder cancer is a heterogeneous disease with different stages, high recurrence, and progression rate. In planning treatment procedures, it is important to know the prevalence of bladder cancer by stages. In the current study, we aimed to estimate the 5-year prevalence of bladder cancer by stages using the Markov model. Methods: This was a simulation study. To estimate the 5-year prevalence of bladder cancer by stages, we used the Markov model with a time horizon of 5 years following diagnosis. We simulated the natural history of bladder cancer using a literature review. We extracted survival rate, stage-specific recurrence, and progression rate using local and international publications and expert opinion. In addition, we used the Iranian life table and extracted probabilities of mortality due to other causes of death. Results: Five-year prevalence of bladder cancer for the year 2018 was estimated at 21,807 patients. Non- muscle-invasive bladder cancer accounted for around 68% of all cases, with 42% in the Ta low-grade stage. About 32% of bladder cancer prevalent cases were muscle-invasive bladder cancer patients, from which about 8% had metastatic tumors. Conclusion: Researchers and policymakers can utilize the findings of this study to conduct economic burden analyses and plan resource allocation. Iran University of Medical Sciences 2022-04-18 /pmc/articles/PMC9448492/ /pubmed/36128281 http://dx.doi.org/10.47176/mjiri.36.37 Text en © 2022 Iran University of Medical Sciences https://creativecommons.org/licenses/by-nc-sa/1.0/This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial-ShareAlike 1.0 License (CC BY-NC-SA 1.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article Rashidian, Hamideh Haghdoost, Ali Akbar Daroudi, Rajabali Raadabadi, Mehdi Ebadzadeh, Mohammad Reza Zendehdel, Kazem Estimating the Prevalence of Bladder Cancer by Stage in Iran as a Developing Country |
title | Estimating the Prevalence of Bladder Cancer by Stage in Iran as a Developing Country |
title_full | Estimating the Prevalence of Bladder Cancer by Stage in Iran as a Developing Country |
title_fullStr | Estimating the Prevalence of Bladder Cancer by Stage in Iran as a Developing Country |
title_full_unstemmed | Estimating the Prevalence of Bladder Cancer by Stage in Iran as a Developing Country |
title_short | Estimating the Prevalence of Bladder Cancer by Stage in Iran as a Developing Country |
title_sort | estimating the prevalence of bladder cancer by stage in iran as a developing country |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448492/ https://www.ncbi.nlm.nih.gov/pubmed/36128281 http://dx.doi.org/10.47176/mjiri.36.37 |
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