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Racial and Treatment Center Differences on Time to Treatment Initiation for Nonsmall Cell Lung Cancer Patients Receiving Radiation Therapy As an Initial Treatment

OBJECTIVE: Because time to treatment has been shown to be associated with increase in the risk of death for Non Small Cell Lung Cancer (NSCLC) patients, we examined the prevalence and magnitude of racial disparities in mean time to radiation therapy (TTRT) for Stage I-III non-small cell lung cancer...

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Autores principales: Rekulapelli, Akhil, Desai, Raj P., Narayan, Aditya, Martin, Linda W., Hall, Richard, Larner, James M., Balkrishnan, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448516/
https://www.ncbi.nlm.nih.gov/pubmed/36081886
http://dx.doi.org/10.1089/heq.2022.0104
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author Rekulapelli, Akhil
Desai, Raj P.
Narayan, Aditya
Martin, Linda W.
Hall, Richard
Larner, James M.
Balkrishnan, Rajesh
author_facet Rekulapelli, Akhil
Desai, Raj P.
Narayan, Aditya
Martin, Linda W.
Hall, Richard
Larner, James M.
Balkrishnan, Rajesh
author_sort Rekulapelli, Akhil
collection PubMed
description OBJECTIVE: Because time to treatment has been shown to be associated with increase in the risk of death for Non Small Cell Lung Cancer (NSCLC) patients, we examined the prevalence and magnitude of racial disparities in mean time to radiation therapy (TTRT) for Stage I-III non-small cell lung cancer patients across a variety of treatment facilities. METHODS: Utilizing the United States National Cancer Database (NCDB), we determined differences in TTRT between different races and different treatment facilities. RESULTS: Concordant with past research, we found that non-White patients and patients treated at academic facilities, regardless of race, have longer mean TTRT, and that racial disparities in TTRT extend across all treatment facilities (all p<0.05). CONCLUSIONS: These findings shed light on the potential presence of and impact of structural racism on patients seeking cancer treatment, and the need for further investigation behind the reasonings behind longer TTI for non-White patients. To elucidate the real-world applicability of these results, further investigation into the societal determinants that perpetuate disparity in time to radiation therapy, and potential interventions in the clinical setting to improve cultural and racial sensitivity among healthcare professionals is recommended.
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spelling pubmed-94485162022-09-07 Racial and Treatment Center Differences on Time to Treatment Initiation for Nonsmall Cell Lung Cancer Patients Receiving Radiation Therapy As an Initial Treatment Rekulapelli, Akhil Desai, Raj P. Narayan, Aditya Martin, Linda W. Hall, Richard Larner, James M. Balkrishnan, Rajesh Health Equity Short Report OBJECTIVE: Because time to treatment has been shown to be associated with increase in the risk of death for Non Small Cell Lung Cancer (NSCLC) patients, we examined the prevalence and magnitude of racial disparities in mean time to radiation therapy (TTRT) for Stage I-III non-small cell lung cancer patients across a variety of treatment facilities. METHODS: Utilizing the United States National Cancer Database (NCDB), we determined differences in TTRT between different races and different treatment facilities. RESULTS: Concordant with past research, we found that non-White patients and patients treated at academic facilities, regardless of race, have longer mean TTRT, and that racial disparities in TTRT extend across all treatment facilities (all p<0.05). CONCLUSIONS: These findings shed light on the potential presence of and impact of structural racism on patients seeking cancer treatment, and the need for further investigation behind the reasonings behind longer TTI for non-White patients. To elucidate the real-world applicability of these results, further investigation into the societal determinants that perpetuate disparity in time to radiation therapy, and potential interventions in the clinical setting to improve cultural and racial sensitivity among healthcare professionals is recommended. Mary Ann Liebert, Inc., publishers 2022-08-18 /pmc/articles/PMC9448516/ /pubmed/36081886 http://dx.doi.org/10.1089/heq.2022.0104 Text en © Akhil Rekulapelli et al., 2022; Published by Mary Ann Liebert, Inc. https://creativecommons.org/licenses/by/4.0/This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Report
Rekulapelli, Akhil
Desai, Raj P.
Narayan, Aditya
Martin, Linda W.
Hall, Richard
Larner, James M.
Balkrishnan, Rajesh
Racial and Treatment Center Differences on Time to Treatment Initiation for Nonsmall Cell Lung Cancer Patients Receiving Radiation Therapy As an Initial Treatment
title Racial and Treatment Center Differences on Time to Treatment Initiation for Nonsmall Cell Lung Cancer Patients Receiving Radiation Therapy As an Initial Treatment
title_full Racial and Treatment Center Differences on Time to Treatment Initiation for Nonsmall Cell Lung Cancer Patients Receiving Radiation Therapy As an Initial Treatment
title_fullStr Racial and Treatment Center Differences on Time to Treatment Initiation for Nonsmall Cell Lung Cancer Patients Receiving Radiation Therapy As an Initial Treatment
title_full_unstemmed Racial and Treatment Center Differences on Time to Treatment Initiation for Nonsmall Cell Lung Cancer Patients Receiving Radiation Therapy As an Initial Treatment
title_short Racial and Treatment Center Differences on Time to Treatment Initiation for Nonsmall Cell Lung Cancer Patients Receiving Radiation Therapy As an Initial Treatment
title_sort racial and treatment center differences on time to treatment initiation for nonsmall cell lung cancer patients receiving radiation therapy as an initial treatment
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448516/
https://www.ncbi.nlm.nih.gov/pubmed/36081886
http://dx.doi.org/10.1089/heq.2022.0104
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