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The present and future of immunocytokines for cancer treatment

Monoclonal antibody (mAb) therapy has successfully been introduced as treatment of several lymphomas and leukemias. However, solid tumors reduce the efficacy of mAb therapy because of an immune-suppressive tumor micro-environment (TME), which hampers activation of effector immune cells. Pro-inflamma...

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Detalles Bibliográficos
Autores principales: Gout, Dennis Y., Groen, Lotte S., van Egmond, Marjolein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448690/
https://www.ncbi.nlm.nih.gov/pubmed/36066630
http://dx.doi.org/10.1007/s00018-022-04514-9