PIM1 promotes hepatic conversion by suppressing reprogramming-induced ferroptosis and cell cycle arrest

Protein kinase-mediated phosphorylation plays a critical role in many biological processes. However, the identification of key regulatory kinases is still a great challenge. Here, we develop a trans-omics-based method, central kinase inference, to predict potentially key kinases by integrating quant...

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Detalles Bibliográficos
Autores principales: Yuan, Yangyang, Wang, Chenwei, Zhuang, Xuran, Lin, Shaofeng, Luo, Miaomiao, Deng, Wankun, Zhou, Jiaqi, Liu, Lihui, Mao, Lina, Peng, Wenbo, Chen, Jian, Wang, Qiangsong, Shu, Yilai, Xue, Yu, Huang, Pengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448736/
https://www.ncbi.nlm.nih.gov/pubmed/36068222
http://dx.doi.org/10.1038/s41467-022-32976-9

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