The mutational signatures of formalin fixation on the human genome

Clinical archives of patient material near-exclusively consist of formalin-fixed and paraffin-embedded (FFPE) blocks. The ability to precisely characterise mutational signatures from FFPE-derived DNA has tremendous translational potential. However, sequencing of DNA derived from FFPE material is kno...

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Detalles Bibliográficos
Autores principales: Guo, Qingli, Lakatos, Eszter, Bakir, Ibrahim Al, Curtius, Kit, Graham, Trevor A., Mustonen, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448750/
https://www.ncbi.nlm.nih.gov/pubmed/36068219
http://dx.doi.org/10.1038/s41467-022-32041-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448750/
https://www.ncbi.nlm.nih.gov/pubmed/36068219
http://dx.doi.org/10.1038/s41467-022-32041-5

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