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Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity

Lactate is a key metabolite produced from glycolytic metabolism of glucose molecules, yet it also serves as a primary carbon fuel source for many cell types. In the tumor-immune microenvironment, effect of lactate on cancer and immune cells can be highly complex and hard to decipher, which is furthe...

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Detalles Bibliográficos
Autores principales:	Feng, Qiang, Liu, Zhida, Yu, Xuexin, Huang, Tongyi, Chen, Jiahui, Wang, Jian, Wilhelm, Jonathan, Li, Suxin, Song, Jiwon, Li, Wei, Sun, Zhichen, Sumer, Baran D., Li, Bo, Fu, Yang-Xin, Gao, Jinming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448806/ https://www.ncbi.nlm.nih.gov/pubmed/36068198 http://dx.doi.org/10.1038/s41467-022-32521-8

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