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Ligand-bound integrin αvβ6 internalisation and trafficking

The integrin αvβ6 is expressed at low levels in most normal healthy tissue but is very often upregulated in a disease context including cancer and fibrosis. Integrins use endocytosis and trafficking as a means of regulating their surface expression and thus their functions, however little is known o...

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Detalles Bibliográficos
Autores principales: Meecham, Amelia, Cutmore, Lauren C., Protopapa, Pantelitsa, Rigby, Lauren G., Marshall, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448872/
https://www.ncbi.nlm.nih.gov/pubmed/36092709
http://dx.doi.org/10.3389/fcell.2022.920303