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Histological and ultrastructural aspects of the tongue in undernourished rats

There are few published studies on the effects of protein-caloric undernourishment on the oral mucosa. OBJECTIVES: The objective of this study is to verify the histological and ultrastructural aspects of the tongue mucosa in protein-caloric undernourished adult rats. MATERIAL AND METHODS: A clinical...

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Autores principales: de Abreu, Marilda Aparecida Milanez Morgado, Weckx, Luc Louis Maurice, Hirata, Cleonice Hitomi Watashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448938/
https://www.ncbi.nlm.nih.gov/pubmed/17143432
http://dx.doi.org/10.1016/S1808-8694(15)30999-X
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author de Abreu, Marilda Aparecida Milanez Morgado
Weckx, Luc Louis Maurice
Hirata, Cleonice Hitomi Watashi
author_facet de Abreu, Marilda Aparecida Milanez Morgado
Weckx, Luc Louis Maurice
Hirata, Cleonice Hitomi Watashi
author_sort de Abreu, Marilda Aparecida Milanez Morgado
collection PubMed
description There are few published studies on the effects of protein-caloric undernourishment on the oral mucosa. OBJECTIVES: The objective of this study is to verify the histological and ultrastructural aspects of the tongue mucosa in protein-caloric undernourished adult rats. MATERIAL AND METHODS: A clinical experimental study was done in thirty Wistar rats, 15 controls and 15 with protein-caloric undernourishment. The last group received ration in small amounts, with a reduced casein content, during 45 days. Rats were weighed every 3 days, from the first (90 days of life) to the last day of a 45-day dietary period, when they were sacrificed. Plasma was used for protein electrophoresis and their tongues were prepared for light and scanning electron microscopy. Analysus of variance and Student's t-test were used for statistical analysis. RESULTS: A significant decrease in weight and in plasma proteins was found in protein-caloric undernourished rats compared to the control group. Histological findings revealed no differences between the two groups and there were no statistically significant differences in the filiform papilla count under the scanning electron microscopy. CONCLUSION: Protein-caloric undernourishment does not cause alterations in the tongue mucosa of adult rats.
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spelling pubmed-94489382022-09-09 Histological and ultrastructural aspects of the tongue in undernourished rats de Abreu, Marilda Aparecida Milanez Morgado Weckx, Luc Louis Maurice Hirata, Cleonice Hitomi Watashi Braz J Otorhinolaryngol Original Article There are few published studies on the effects of protein-caloric undernourishment on the oral mucosa. OBJECTIVES: The objective of this study is to verify the histological and ultrastructural aspects of the tongue mucosa in protein-caloric undernourished adult rats. MATERIAL AND METHODS: A clinical experimental study was done in thirty Wistar rats, 15 controls and 15 with protein-caloric undernourishment. The last group received ration in small amounts, with a reduced casein content, during 45 days. Rats were weighed every 3 days, from the first (90 days of life) to the last day of a 45-day dietary period, when they were sacrificed. Plasma was used for protein electrophoresis and their tongues were prepared for light and scanning electron microscopy. Analysus of variance and Student's t-test were used for statistical analysis. RESULTS: A significant decrease in weight and in plasma proteins was found in protein-caloric undernourished rats compared to the control group. Histological findings revealed no differences between the two groups and there were no statistically significant differences in the filiform papilla count under the scanning electron microscopy. CONCLUSION: Protein-caloric undernourishment does not cause alterations in the tongue mucosa of adult rats. Elsevier 2015-10-19 /pmc/articles/PMC9448938/ /pubmed/17143432 http://dx.doi.org/10.1016/S1808-8694(15)30999-X Text en © . https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Article
de Abreu, Marilda Aparecida Milanez Morgado
Weckx, Luc Louis Maurice
Hirata, Cleonice Hitomi Watashi
Histological and ultrastructural aspects of the tongue in undernourished rats
title Histological and ultrastructural aspects of the tongue in undernourished rats
title_full Histological and ultrastructural aspects of the tongue in undernourished rats
title_fullStr Histological and ultrastructural aspects of the tongue in undernourished rats
title_full_unstemmed Histological and ultrastructural aspects of the tongue in undernourished rats
title_short Histological and ultrastructural aspects of the tongue in undernourished rats
title_sort histological and ultrastructural aspects of the tongue in undernourished rats
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448938/
https://www.ncbi.nlm.nih.gov/pubmed/17143432
http://dx.doi.org/10.1016/S1808-8694(15)30999-X
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